Lymphomas affecting the submandibular glands.

BACKGROUND: Lymphomas affecting the submandibular glands are very uncommon and few reports are currently available in the literature. Therefore, the aim of the current study is to describe the clinical and microscopic features of an original series of lymphomas affecting the submandibular glands. MATERIAL AND METHODS: The pathology files of two institutions were searched for lymphoma cases affecting the submandibular glands. The original hematoxylin and eosin, and immunohistochemical slides were revised by a pathologist for diagnosis confirmation following the revised 4th edition of the World Health Organization classification of tumours of haematopoietic and lymphoid tissues. Clinical data regarding age, sex, clinical manifestation, treatment, follow-up and status at last appointment were retrieved from the patients' medical charts. RESULTS: During the period investigated, 16 cases were included in the study. Females predominated (10:6) with a mean age of 57.8 years-old. Tumors usually presented as asymptomatic swellings. MALT lymphoma represented the most common subtype, followed by diffuse large B cell lymphoma and follicular lymphoma. Three patients died, one of them affected by plasmablastic lymphoma, one by DLBCL and one by MALT lymphoma. CONCLUSIONS: Low-grade B cell lymphomas predominate in the submandibular glands, but DLBCL and other subtypes may also be rarely diagnosed in this salivary gland.

Longitudinal changes in anthropometric characteristics of elderly Europeans. SENECA Investigators.

OBJECTIVE: Assess longitudinal changes in height, body weight, triceps skinfold thickness and circumferences in elderly Europeans. DESIGN: Longitudinal study including baseline measurements taken in 1988/1989 which were repeated in 1993. SETTING: Baseline and follow-up data were collected in nine European research towns: Hamme/Belgium (H/F), Roskilde/Denmark (R/DK), Haguenau/France (H/F), Romans/France (R/F), Padua/Italy (P/I), Culemborg/the Netherlands (C/NL), Vila Franca de Xira/Portugal (V/P), Betanzos/Spain (B/E), Yverdon/Switzerland (Y/CH). Single 1993 measurements were carried out in 4 towns: Coimbra/Portugal (C/P), Marki/Poland (M/PL), Ballymoney-Limavady-Portstewart/Northern Ireland/UK (BLP/NI/UK), Mansfield/Connecticut/USA (M/CT/USA). SUBJECTS: Using standardized methodologies data were collected from a random stratified sample of elderly men and women born between 1913 and 1918 including a total of 1242 subjects in 1993. RESULTS: At most sites stature had decreased by 1-2cm. Median weight changed by -1.5 kg to -3.5 kg in only three towns. An increase of at least 5 kg of body weight had taken place in 9% of men and 6% of women whereas 16% of both men and women had lost at least 5 kg of their baseline weight. Serial changes in triceps skinfold thickness, arm circumference and waist-to-hip ratio were small. CONCLUSIONS: Height declined with age. Median changes in other anthropometric characteristics of interest were small. These changes resulted from both considerable gains and losses of body weight in a significant proportion of the SENECA populations.