ABSTRACT
Hepatocellular carcinoma and other tumours of the liver are extremely rare in Wilson's disease. We report a patient who presented with a cholangiocarcinoma associated with Wilson's disease. The literature review underlines that patients with Wilson's disease should be considered at risk of hepatocellular carcinoma, cholangiocarcinoma and undifferentiated carcinoma in the liver. Risk factors seem to be long disease duration and probably a poor observance to therapy. A liver imaging should be included in the follow-up of patients with Wilson's disease.
Subject(s)
Bile Duct Neoplasms/complications , Bile Ducts, Intrahepatic , Cholangiocarcinoma/complications , Hepatolenticular Degeneration/complications , Adult , Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Bile Duct Neoplasms/diagnosis , Bile Duct Neoplasms/drug therapy , Cholangiocarcinoma/diagnosis , Cholangiocarcinoma/drug therapy , Fatal Outcome , Hepatolenticular Degeneration/diagnosis , Hepatolenticular Degeneration/drug therapy , Humans , Male , Risk FactorsABSTRACT
We report a case of massive pulmonary embolism during cyanoacrylate glue endoscopic injection in a patient with gastric varices from portal hypertension. A review of the literature and results in an animal model show the physiopathology and risk factors associated with this endoscopic procedure.
Subject(s)
Cyanoacrylates/adverse effects , Esophageal and Gastric Varices/therapy , Pulmonary Embolism/chemically induced , Acute Disease , Cyanoacrylates/administration & dosage , Fatal Outcome , Humans , SclerotherapyABSTRACT
Bleeding from a pseudoaneurysm is a rare complication of chronic pancreatitis. We present two cases of ruptured pseudoaneurysms of the hepatic arteries. The first case involved a pancreatic pseudocyst that ruptured in the duodenum and the second resulted in an intrahepatic hematoma that compressed the bile tract causing secondary hemobilia. Angiographic embolization was the primary treatment in both cases, with surgery for the first patient and later radiological drainage in the second. The hemorrhage was controlled in both cases despite the severe prognosis and high mortality in these cases.
