ABSTRACT
No disponible
Subject(s)
Humans , Male , Middle Aged , Leiomyosarcoma/surgery , Adrenal Gland Neoplasms/surgery , Pulmonary Emphysema/diagnosis , Incidental Findings , Tomography, X-Ray Computed , Magnetic Resonance SpectroscopySubject(s)
Adrenal Gland Neoplasms/diagnosis , Leiomyosarcoma/diagnosis , Humans , Male , Middle AgedABSTRACT
Objetivos. Presentar un caso de prostatitis con retención aguda de orina como manifestación inicial poco frecuente de granulomatosis de Wegener. Métodos. Se presenta el caso de un varón de 48 años con un cuadro de prostatitis de 10 días de evolución, que presentó retención de orina, con respuesta parcial al tratamiento antibiótico, y con niveles elevados de anticuerpos citoplasmáticos contra los neutrófilos con patrón citoplasmático y estudio anátomo-patológico de la biopsia prostática compatible con granulomatosis de Wegener. Resultados. Tras el inicio de tratamiento mediante glucocorticoides y ciclofosfamida se observa mejoría notable de los síntomas hasta su desaparición. A los 3 meses inicia clínica pulmonar y de vías aéreas superiores, precisando para el control de sus síntomas dosis mayores de ciclofosfamida. Conclusiones. La granulomatosis de Wegener es una entidad multisistémica cuya forma de presentación como prostatitis con retención de orina es poco frecuente (AU)
Objectives. We present a case of prostatitis with acute urinary retention as a rare initial manifestation of Wegener's granulomatosis. Methods. The case was a 48-year-old male with symptoms of prostatitis over 10 days. The patient presented urinary retention, with partial response to antibiotic treatment. High levels of cytoplasmic antineutrophil cytoplasmic antibody and a prostatic biopsy were compatible with Wegener's granulomatosis. Results. After starting treatment with glucocorticoids and cyclophosphamide, a significant improvement to the point of disappearance of symptoms was observed. At 3 months pulmonary and upper airway symptoms began, requiring higher doses of cyclophosphamide to control symptoms. Conclusions. Wegener's granulomatosis is a multisystem entity whose presentation as prostatitis with urinary retention is rare (AU)
Subject(s)
Humans , Male , Middle Aged , Granulomatosis with Polyangiitis/complications , Granulomatosis with Polyangiitis/diagnosis , Granulomatosis with Polyangiitis/drug therapy , Urinary Retention/complications , Urinary Retention/diagnosis , Glucocorticoids/therapeutic use , Cyclophosphamide/therapeutic use , Granulomatosis with Polyangiitis/physiopathology , Prostatitis/complications , Prostatitis/diagnosis , Cytoplasmic Granules/pathology , Receptors, Cytoplasmic and Nuclear , Methylprednisolone/therapeutic useABSTRACT
OBJECTIVES: We present a case of prostatitis with acute urinary retention as a rare initial manifestation of Wegener' Granulomatosis. METHODS: The case was a 48-year-old male with symptoms of prostatitis over ten days. The patient presented urinary retention, with partial response to antibiotic treatment. High levels of cytoplasmic antineutrophil cytoplasmic antibody and a prostatic biopsy were compatible with Wegener' Granulomatosis. RESULTS: After starting treatment with glucocorticoids and cyclophosphamide, a significant improvement to the point of disappearance of symptoms was observed. At 3 months pulmonary and upper airway symptoms began, requiring higher doses of cyclophosphamide to control symptoms. CONCLUSIONS: Wegener's Granulomatosis is a multisystem entity whose presentation as prostatitis with urinary retention is rare.
