ABSTRACT
26 persons, having high level of erythrocytes with micronuclei were distinguished among clinically healthy people. While examining their health changes were registered in the systolic and pulse pressures, number of T-suppressors and T-helpers, natural killers, level of immunoglobulins and immune complexes, phagocytosis activity and peroxidases reaction of the leukocytes. Increase in the level of the cytogenetic aberrative lymphocytes was observed in all the cases. DNA-reparative synthesis was reduced only in 5 persons.
Subject(s)
Erythrocytes/ultrastructure , Immunity/physiology , Adolescent , Adult , Antigen-Antibody Reactions/immunology , Blood Pressure/physiology , DNA Repair/physiology , Humans , Immunoglobulins/metabolism , Killer Cells, Natural/physiology , Leukocyte Count , Micronucleus Tests , T-Lymphocytes, Helper-Inducer/physiology , T-Lymphocytes, Regulatory/physiologyABSTRACT
Complex examination of oil industry workers and those engaged in nonproductive area (control group) was undertaken. It was established that in both groups there were persons with a high level of cells with cytogenetic disturbances (micronuclear test). However, as opposed to control group, oil industry workers had higher levels of systolic and pulse pressure. Besides it was shown that after 12 hours of work at an oil field under winter conditions in the north area of the Tomsk Region they had higher body temperature. It appeared that these persons primarily had the longest term of professional service. Further examination of persons with especially high level of micronuclei cells showed that they had elevated lymphocyte amount with chromosome impairments and some parameters of T- and B-immunoreactivity, phagocytosis and activity of normal killer cells were changed.