Laser-assisted resection of a giant pulmonary chondrohamartoma--a case report.

A rare case of a giant pulmonary chondromatous hamartoma (15 cm, 1350 g) resected by a new laser system (Nd:YAG, 1318 nm, 40 W) is presented. The laser management of a hamartoma resection--the largest reported to date in the literature--is presented here.

Resection of multiple lung metastases--where are the limits?

Multiple lung metastases present a serious and challenging problem with increasing incidence for thoracic surgeons. In the lung metastasis management a significant role belongs to laser lung-parenchyma-saving resection. This parenchyma saving technique allows a removal of significant higher number of lung nodules in comparison to conventional techniques (stapler, clamp resection). Performing the lung metastasectomy by this manner, the only remaining question is the limitation of this technique. In this retrospective study, the results after Nd:YAG Laser (1318 nm, 40 Watt) interventions are being presented, the limitations of this technique are being discussed (Tab. 3, Fig. 4, Ref. 9).

Central airways stenoses management--a single institution experience.

Tracheal stenosis is a serious, life-threatening disease with an increasing tendency. The number of complicated tracheal lesions, where resection and anastomosis can not be performed, still increases and the situation requires solution by endoprosthesis. Consequent the management of such complicated obstructive tracheal lesions is individual and time-consuming. The main objective of this study is to review the single institution experience with central airways stenosis treatment and to define the role of endotracheal stenting in tracheal reconstruction surgery. This study presents the retrospective analysis of tracheal stenosis reconstruction by means of our own modification of Montgomery T-tube. (Tab. 3, Fig. 3, Ref. 12.)

Complications of video-mediastinoscopy--successful management in four cases.

The authors describe complications of video-mediastinoscopy in a number of clinical cases and present case reports of four patients, where this complication occurred. The following types of complications were recorded: one case of esophageal perforation, one case of tracheal lesion and two cases of massive bleeding from central greater vessel. Possibilities of treatment methods of these complications, possible ways how to manage and decrease the incidence of life-threatening complication are being discussed in this paper. (Fig. 5, Ref. 9.).

Initial experience with lung transplantation in Slovakia--an example for successful bilateral cooperation between countries.

OBJECTIVE: To review initial experiences, results of single lung transplantation (SLT) and double lung transplantation (DLT) on the basis of bilateral cooperation between Slovakia and Austria. PATIENTS AND METHODS: During the period between July 1998 and January 2003 ten patients from Slovakia underwent lung transplantation in Vienna, Austria. There were 7 males and 3 females with an age range from 21 to 48 years. Eight patients underwent double lung transplantation, two patients had single lung transplantation. Indications were: pulmonary fibrosis in 2, cystic fibrosis in 2, emphysema in 2, primary pulmonary hypertension (PPH) in 4 cases. In the PPH patients (n = 4) and in the patients with cystic fibrosis (n = 2), bilateral lung transplantation under ECMO support was performed. One patient (n = 1) with postradiative pulmonary fibrosis and intracardial myxoma underwent bilateral lung transplantation under cardiopulmonary bypass. Only three patients (e.i. the two with emphysema and one with pulmonary fibrosis) underwent lung transplantation without any intraoperative circulatory support. RESULTS: No perioperative mortality was recorded. Two patients died in late postoperative period: one due to multiorgan failure on 93rd day after DLT, the other one--on a liver failure caused by cirrhosis after 2.5 years after LTX. All the remaining eight patients, but the two ones who underwent LTX several days ago, are with improved functional status in full work activity. The follow up period for all patients ranges between 10 days and 54 months. CONCLUSION: Both unilateral and bilateral lung transplantations are accepted treatment modalities in patients with end-stage pulmonary disease. Bilateral cooperation for such countries as Slovakia (with limited possibilities) offers a unique example of possible and successful way how to deal with such demanding procedures. (Tab. 3, Fig. 2, Ref. 19.).

Prostacyclins in pulmonary hypertension treatment.

Pulmonary hypertension is a rare, treacherous disease affecting the lungs and heart. Elevated pulmonary artery pressure (above 2.67 kPa) and pathologically high pulmonary vascular resistance are characteristic for this disease. This disease is insidiously progressive and often leads to sudden death mainly in middle and younger middle ages. Exhausting the traditional conservative means of treatment, lung/heart-lung transplantation offers the only possibility to improve the quality of patient's life. Nowadays more and more reports about the successful application of intravenous prostacyclin for treatment of this disease appear in specialized literature. Epoprostenol (prostacyclin PGI2) represents a new, potent drug for the treatment of pulmonary hypertension. The objective of this paper is to introduce prostacyclin PGI2 to experts and demonstrate new possibilities, procedures, trends in treatment of pulmonary hypertension. (Tab. 1, Ref. 30.).

Extracorporeal membrane oxygenation in lung transplantation.

Lung transplantation has become an accepted surgical modality. As the primary pulmonary graft failure accounts for almost one third of early deaths, new possibilities to positively influence this life-threatening complication had been searched for. extracorporeal membrane oxygenation (ECMO) offers an unique advantage of overcome the demanding peri- and postoperative period. The authors present the advantage of ECMO use, introduce a review of experience with its application in lung transplantation. (Fig. 2, Ref. 36.)

[The complications of pulmonary resection treatment of lung cancer]. / The complications of pulmonary resection treatment of lung cancer.

This article discusses the complications of the pulmonary resection treatment in lung cancer. A significant decrease in incidence of cardiovascular and respiratory complications has already been achieved during the last decades. However, infectious complications, mainly pneumonias and postpneumonectomy empyemas still remain and belong among treacherous complications which are often associated with significant mortality. This article devotes special attention to the possibilities of influencing and decreasing the incidence of these complications.

Lung transplantation today.

Lung transplantation has become an accepted surgical modality, and it is indicated in patients with a long-term benign pulmonary disease in stage when all the other therapeutic possibilities failed. Nowadays it presents a real possibility to significantly improve the quality of life. Success, (mainly in the last decade), establishing international professional centers, national coordinations, shifts transplantation towards the standard treatment procedures. The objective of the paper is to offer an overview of the international activities, trends and results in the area of lung transplantation. Authors present a review of the current situation based on their own experiences gained from the bilateral cooperation with Vienna Transplant Group. (Tab. 4, Fig. 4, Ref. 19.)

Circumstances of bronchiolitis obliterans development after lung transplantation: analysis of risk factors.

Bronchiolitis obliterans after lung transplantation is the major factor which limits the long term survival. It affects 35-68% of those patients who survive longer than 3 months. Nowadays, the results of treatment and evaluation of bronchiolitis obliterans risk factors are not very encouraging. Although several risk factors of the development of bronchiolitis obliterans have already been identified, their role and importance have not been clearly defined yet. The objective of this article is to give an overview of the current international knowledge in treatment strategies and analyse to international trends in the research of risk factors of the development of this complication together with available results. Special attention is given to donor and recipient risk factors. (Tab. 2, Fig. 1, Ref. 32.)

[Tracheal stenosis and its treatment]. / Stenóza trachey a jej liecba.

A group of 89 patients suffering from tracheostenosis was studied in the period from January 1990 to January 1999. Surgical procedure on trachea was performed in 63 patients with postintubation (posttracheostomic) stenosis, in 6 patients with direct tracheal trauma, in 9 with tracheoesophageal fistula, in 7 with malignant stenosis, in 3 with postinflammatory subglottic stenosis. In the treatment of tracheal stenosis a set of methods was used ranging from laser and tracheal endoproteses, through cartilage implantation and plastic reconstruction of tracheal defects to extensive segmental resections. In a group of 50 patients with segmental resection in 43 (%) of them the result was good, in 2 (4%) of them satisfying, in 4 (8%) of them temporary brace (on T-cannule) persists, 1 patient died in postoperative period (2%). In a group of 39 patients with combined conservative treatment in 18 patients good results were reached (43.8%), in 6 satisfying (15.4%), in 13 of them temporary brace (on T-cannule) persists (33.3%) and 2 died in postoperative period (5.1%). In conclusion the results of this work suggest that the most frequent indication for surgical treatment is postintubation (postracheostomy) stenosis and that segmental trachea resection has priority in the treatment of tracheal stenoses. (Tab. 2, Ref. 18.)

Impact of different coverage techniques on incidence of postpneumonectomy stump fistula.

OBJECTIVE: Postpneumonectomy bronchial stump fistula (PBSF) is a serious complication with a reported incidence between 0 and 12%. The aim of this retrospective study was to investigate the effectiveness of different coverage techniques of the bronchial stump applied in a consecutive series of pneumonectomies in avoiding this particular problem. METHODS: Between 1/87 and 10/97, 129 patients (90 male, 39 female, mean age 57.8 years, range: 15-78 years) underwent pneumonectomy by one surgeon (W.K.). In 14 patients, additional resection procedures were performed (aorta n = 6, vena cava n = 5, thoracic wall n = 3). In all patients with malignancies (n = 123), mediastinal lymphadenectomy was routinely added to the procedure. Bronchial stump closure was performed by means of stapling devices in all patients. Coverage of the bronchial stump was performed with a generous pedicled pericardial flap and concomitant reconstruction of the pericardium with Vicryl mesh (n = 50), with a portion of the posterior pericardium (n = 16), with the azygos vein (n = 12), with surrounding mediastinal tissue (n = 25), with pleura (n = 16), or with intercostal muscle flap (n = 3); no coverage at all was performed in seven patients. In all patients with high risk for development of PBSF, i.e. patients who received any form of neoadjuvant therapy or had extended resections, the pericardial flap technique was used. RESULTS: Perioperative mortality was 5.4% (n = 7) and five patients (3.9%) experienced significant perioperative complications, with one of them directly related to the method of bronchial stump coverage (cardiac tamponade due to the use of a too small Vicryl mesh for reconstruction of the pericardium). Follow-up was 96.1% complete (five patients were lost to follow-up). Fourty-seven patients (36.4%) died late after operation (mean 19+/-13 months, median 17 months), mainly due to recurrence of their underlying malignant disease. PBSF occurred in one patient only (0.8%), 2 weeks after operation (coverage with pleura). No PBSF was seen in the long term follow-up period. CONCLUSION: Coverage of the bronchial stump contributes to a low incidence of PBSF. In view of the fact, that this serious complication was completely avoided in the pericardial flap group (used in patients with expected higher risk for PBSF), this particular technique seems to offer the best results.

Bilateral lung transplantation via two sequential anterolateral thoracotomies.

OBJECTIVE: Bilateral anterior trans-sternal thoracotomy (clam shell incision) is the standard approach used for bilateral sequential lung transplantation (BLTX). The morbidity of this large incision can be considerable. Two separate sequential anterolateral thoractomies represent a less invasive approach. METHODS: The value of this approach was investigated in a prospective series of 22 consecutive patients who received BLTX between June 1997 and July 1998. Their underlying diseases were COPD (n = 16), cystic fibrosis (n = 4) and other (n = 2). All patients underwent BLTX through two anterolateral thoracotomies, without the use of cardiopulmonary bypass. The anterior mediastinum and the sternum with all the surrounding tissue were left completely intact. Twenty-one patients underwent spirometrical examination during the postoperative in-hospital stay. Follow-up is 7+/-4 months (range: 3 to 15). RESULTS: The only intraoperative complication was severe reperfusion edema of the first transplanted lung seen in one patient at the end of the operation, which required pneumonectomy during the same session. All other operations were uneventful. The difference between the cold ischemic time of the first and second transplanted lung was 83+/-17 min. Median intubation duration, ICU- and in-hospital-stay were 1.5, 5 and 20 days, respectively (ranges: 1 to 96, 2 to 96 and 15 to 96, respectively). One major perioperative complication occurred and was due to gross donor/recipient size mismatch: the patient required lobectomy of the consolidated right upper lobe 11 days after transplantation. In 19 patients (86.4%), this less extensive incision allowed early postoperative mobilization, which resulted in good ventilatory performance, with VC of 53+/-15 and FEV1 of 60+/-20% of the predicted, respectively, at the first spirometry, 3 weeks after the operation. Three months survival was 100%. CONCLUSION: The bilateral sequential anterolateral thoracotomy represents a safe and minimal invasive approach for BLTX compared with the clam shell incision. It minimizes the operative trauma, improves postoperative functional recovery and prevents the potential spread of unilateral complications to the other pleural cavity.

[Surgical complications of tracheal intubation--tracheal rupture]. / Chirurgická komplikácia tracheálnej intubácie--ruptúra trachey.

Authors present case report of 47-year-old woman with a rupture of trachea in its lower part after an intubation with a double-lumen tube without any problems. Tracheal lesion was discovered at the end of operation after an extirpation of mediastinal tumor and wedge resection of lung during the examination of hermeticity of lung mechanical suture. Rupture was cured by suture resorbable monofilamental material. Development after operation wasn't any different than a common lung resection. In the lecture authors discuss the possible causes of tracheal rupture, different kinds of therapy, and complications.