ABSTRACT
The problems of the optimization of the therapeutic action of probiotics are discussed. Their use in combination with vitamin-enriched food additives is recommended. Balsams "Beryozka" and "Zolotoi koren" have been found to promote the adhesive capacity of bifidobacteria and lactobacteria. At the same time "Zolotoi koren" also enhances the functional activity of lactobacilli. The increase of the adhesive capacity and metabolic activity of automicroflora on one hand and the pronounced biostimulating effect of the balsams on the other hand may ensure a sufficiently high level of the colonization resistance of the body.
Subject(s)
Bacterial Adhesion/drug effects , Balsams/therapeutic use , Dietary Supplements , Probiotics/therapeutic use , Bifidobacterium/drug effects , Colony Count, Microbial , Lactobacillus/drug effects , Microbial Sensitivity Tests , Vitamins/therapeutic useSubject(s)
Air Pollutants, Occupational/adverse effects , Aniline Compounds/adverse effects , Ascorbic Acid Deficiency/chemically induced , Chemical Industry , Coloring Agents/adverse effects , Occupational Diseases/chemically induced , Vitamin B Deficiency/chemically induced , Adult , Ascorbic Acid Deficiency/drug therapy , Humans , Middle Aged , Occupational Diseases/drug therapy , Organic Chemicals , Russia , Vitamin B Deficiency/drug therapy , Vitamins/therapeutic useABSTRACT
The influence of the isocalorific rations with decreased (10%) or increased (32%) protein content, and addition of cystine, methionine and glutamic acid (100 mg/kg) on metabolism of vitamins B2, B6 and PP was studied in rats under conditions of experimental chronic aniline intoxication. Increased protein amount in the diet and addition of amino acids sharply raise vitamin B6 requirement; vitamin B2 requirement grows with the increase of protein fraction and methionine and glutamic acid addition. Providing with vitamin PP under these conditions rises. Chronic aniline intoxication negatively influences the vitamin status of the test animals. Providing with vitamin B6 is most sharply decreased. Glutamic acid shows "saving" influence with respect to vitamin B2. The effect of chronic aniline intoxication on providing with vitamin PP is most manifested in the redistribution of oxidized and reduced nicotine amide coenzymes in the liver in the direction of a relative growth of reduced NAD and NADP concentrations.
