ABSTRACT
On 7 January 2011, a six year-old child living in a Roma community near Seville, southern Spain, was hospitalised with measles. Contact tracing identified a probable index case with onset of symptoms on 20 December 2011 and several unreported cases among children under the age of 15 years in the same town. The outbreak initially spread in districts in the city of Seville with a high proportion of Roma residents, and later to other cities and towns in Andalusia. While some towns experienced wide spread of the disease with significant clusters of cases, most of the affected locations saw non-clustered cases or very few secondary cases. The outbreak resulted in 1,759 confirmed or probable cases of which 393 (19%) required hospitalisation. Measles virus of genotype D4 was diagnosed in more than half of the cases. Significant differences (p<0.0001) by age group were found between clustered and non-clustered cases. The highest proportion of clustered cases occurred in the age group of 5-14 yearolds, while the highest proportion of non-clustered cases was seen in those older than 29 years. The last confirmed case related to this outbreak was reported on 20 August 2011.
Subject(s)
Disease Outbreaks , Immunization Programs , Measles Vaccine/administration & dosage , Measles virus , Measles/epidemiology , Adolescent , Adult , Ambulatory Care Facilities/standards , Child , Child, Preschool , Contact Tracing/statistics & numerical data , Contact Tracing/trends , Disease Notification , Disease Outbreaks/prevention & control , Disease Outbreaks/statistics & numerical data , Drug Administration Schedule , Female , Health Personnel/standards , Hospitalization/statistics & numerical data , Hospitalization/trends , Humans , Immunization Programs/organization & administration , Immunization Programs/standards , Infant , Infant, Newborn , Measles/diagnosis , Measles/prevention & control , Measles virus/immunology , Measles virus/isolation & purification , Measles virus/pathogenicity , Medically Underserved Area , Real-Time Polymerase Chain Reaction , Sentinel Surveillance , Sequence Analysis, DNA , Spain/epidemiology , WorkforceABSTRACT
Between March and May of 2011, a cluster of three fatal cases of meningococcal sepsis occurred in Andalusia, Spain, in a municipality with a population of around 20,000 inhabitants. The cases were in their mid-teens to early thirties and were notified to the epidemiological surveillance system of Andalusia (Sistema de Vigilancia Epidemiológica de Andalucía, SVEA) during a 68-day period from March through May 2011. All three were infected with the same strain of Neisseria meningitidis serogroup C genosubtype VR1:5-1;VR2:10-8. None of the cases had been previously vaccinated against N. meningitidis serogroup C. Antibiotic post-exposure chemoprophylaxis was administered to close contacts of every diagnosed case. Once the cluster was confirmed, the local population was informed through the media about the control measures taken by the health authorities. The vaccination history against N. meningitidis serogroup C of the population under 25 years-old in the municipality was checked. Vaccination was offered to unimmunised individuals younger than 25 years of age and an additional dose of vaccine was offered to those who had been vaccinated between 2000 and 2006 with a vaccination schedule of three doses before the first year of age. No further cases occurred since the beginning of these actions.
Subject(s)
Disease Outbreaks/prevention & control , Meningococcal Infections/diagnosis , Neisseria meningitidis, Serogroup C/isolation & purification , Adolescent , Adult , Anti-Bacterial Agents/therapeutic use , Cluster Analysis , Contact Tracing , Disease Notification , Fatal Outcome , Female , Humans , Male , Meningococcal Infections/drug therapy , Meningococcal Infections/epidemiology , Meningococcal Infections/prevention & control , Meningococcal Vaccines/administration & dosage , Neisseria meningitidis, Serogroup C/genetics , Post-Exposure Prophylaxis , Retrospective Studies , Sepsis/etiology , Serotyping , Spain/epidemiology , Urban Population , Vaccination , Young AdultABSTRACT
In September and October 2010, 13 primary measles cases were identified among unvaccinated persons aged between 9 and 32 years (median: 16.5) in 11 districts in Germany. All cases had attended meetings in Taizé, France. This outbreak illustrates the risk of long distance spread of infectious diseases associated with international mass gatherings, and underlines the importance of closing immunisation gaps against measles by vaccinating non-immune adolescents and young adults.
Subject(s)
Disease Outbreaks , Measles virus/isolation & purification , Measles-Mumps-Rubella Vaccine/administration & dosage , Measles/epidemiology , Adolescent , Adult , Age Distribution , Child , Child, Preschool , Disease Notification , Genotype , Humans , Infant , Measles/prevention & control , Measles/transmission , Measles virus/genetics , Population Surveillance , Spain/epidemiology , Vaccination/statistics & numerical data , Young AdultABSTRACT
In Andalusia, Spain, the pandemic influenza A(H1N1)v virus has spread throughout the community, being the dominant influenza strain in the season so far. The current objective of the Andalusia Health Service is focussed on the mitigation of the health and social impact by appropriate care of the patients at home or in health centres. The 2009-10 seasonal influenza epidemic started early compared with to previous seasons. This article analyses the influenza A(H1N1)v situation in Andalusia until the week 39/2009.
