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Ter Arkh ; 61(9): 82-5, 1989.
Article in Russian | MEDLINE | ID: mdl-2595593

ABSTRACT

Disorders of heart rhythm and conduction were characterized clinically and by electrocardiography in 82 patients with dilated and hypertrophic cardiomyopathies. Based on an analysis of blood lymphocyte cytochemistry energy-deficient conditions of the myocardium were identified in the patients examined. In order to correct the metabolic shifts in the myocardium, use was made of a coenzymic medicamentous complex including pyridoxalphosphate, cobamamide and phosphadene. The complex indicated was shown to potentiate the action of antiarrhythmic agents employed in the treatment of idiopathic cardiomyopathies.


Subject(s)
Arrhythmias, Cardiac/drug therapy , Cardiomyopathy, Dilated/drug therapy , Cardiomyopathy, Hypertrophic/drug therapy , Coenzymes/therapeutic use , Adult , Aged , Arrhythmias, Cardiac/enzymology , Arrhythmias, Cardiac/etiology , Cardiomyopathy, Dilated/complications , Cardiomyopathy, Dilated/enzymology , Cardiomyopathy, Hypertrophic/complications , Cardiomyopathy, Hypertrophic/enzymology , Drug Evaluation , Drug Therapy, Combination , Energy Metabolism/drug effects , Female , Humans , Lymphocytes/drug effects , Lymphocytes/enzymology , Male , Middle Aged , Myocardium/enzymology , Syndrome
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