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2.
Clin Exp Dermatol ; 37(5): 505-8, 2012 Jul.
Article in English | MEDLINE | ID: mdl-22439885

ABSTRACT

Cutaneous sarcomatoid carcinoma is a high-grade malignancy. We describe a clinical case of an aggressive sarcomatoid carcinoma in an 87-year-old woman, who presented to the outpatients department with a haemorrhagic nodule on the dorsum of her right hand. By the time of excision 3 weeks later, the nodule had enlarged to 100 × 90 × 65 mm in size. On histological examination, a poorly differentiated carcinoma was seen, with both carcinomatous and sarcomatous elements, in keeping with a sarcomatoid carcinoma. The tumour was positive for cytokeratin, epithelial, smooth-muscle actin, and vimentin stains. Two months later, the patient presented with a recurrent growth on the excised scar along with numerous large right axillary lymph nodes. A right axillary dissection along with excision of the growth confirmed tumour recurrence with metastasis to lymph nodes. Soon after, the patient developed cerebral metastasis, which proved fatal. This case thus highlights the aggressive potential of sarcomatoid carcinoma.


Subject(s)
Carcinosarcoma/pathology , Hand , Skin Neoplasms/pathology , Aged, 80 and over , Carcinosarcoma/secondary , Fatal Outcome , Female , Humans , Lymphatic Metastasis
3.
Eur J Surg Oncol ; 38(4): 346-51, 2012 Apr.
Article in English | MEDLINE | ID: mdl-22264775

ABSTRACT

BACKGROUND: The National Institute of Clinical Excellence (NICE) published Improving Outcome Guidance in 2006 defining urgent referral criteria for soft tissue sarcoma (STSs) with the twin aims of improving diagnostic accuracy and overall outcome. Despite these guidelines inadvertent excisions of soft tissue sarcomas continue to occur with alarming frequency, potentially compromising patient outcomes. OBJECTIVE: We reviewed the East Midlands Sarcoma Service experience of treating inadvertent excision of STSs and highlight the patient profile, referral pattern, subsequent management and oncological outcome associated with inadvertent resection. METHODS: Patients were identified from our sarcoma database and a retrospective case note review performed. RESULTS: Over a 3-year period, 42 patients presented to our specialist centre after unplanned excision of soft tissue sarcomas. There were 29 men and 13 women, with a mean age at presentation of 59 years (19-90). 50% of the tumours were located in lower extremity, 33% around the trunk and 17% in the upper extremity. The unplanned surgery was most commonly from general surgeons, plastic surgeons, orthopaedic surgeons, general practitioners followed by vascular surgeons. Re-resection was undertaken in 40 cases to achieve clear margins with residual tumour present in 74% of cases. Limb salvage surgery was not possible in 5 cases. CONCLUSION: Unplanned excision of sarcoma by non-oncologic surgeons remains a problem. It appears that it is equally prevalent in varied surgical community and general practitioners. Excision of large or deep solid soft tissue masses without tissue diagnosis is unacceptable.


Subject(s)
Benchmarking , Practice Patterns, Physicians' , Referral and Consultation/standards , Sarcoma/diagnosis , Sarcoma/surgery , Unnecessary Procedures/statistics & numerical data , Adult , Aged , Aged, 80 and over , Databases, Factual , England , Female , Humans , Male , Middle Aged , Referral and Consultation/statistics & numerical data , Retrospective Studies , State Medicine/standards , Young Adult
5.
J Plast Reconstr Aesthet Surg ; 62(12): 1661-5, 2009 Dec.
Article in English | MEDLINE | ID: mdl-18993122

ABSTRACT

Accurate preoperative localisation of deep inferior epigastric artery perforator (DIEaP) provides optimal surgical planning for DIEaP flaps. Cross-sectional imaging by contrast-enhanced magnetic resonance angiography (CE-MRA) has advantages over previously described techniques for perforator imaging including reduced radiation exposure and better muscle to vessel contrast. A retrospective series of 10 unilateral free breast reconstructions following preoperative CE-MRA of the anterior abdominal wall is presented. Mean age of the patients at the time of surgery was 50.3 years (range 44-63 years). An average of 2.8 perforators per study (range 1-5) was identified. Mean perforator luminal diameter was 2.6mm (1.4-4.0mm) with a mean intramuscular course length of 22.3mm (6.4-51.9 mm). Perforator course length was classified as 17% long intramuscular course (>4 cm), 80% short intramuscular course (<4 cm) and 3% paramedian. In all 10 patients, DIEaP flaps were successfully elevated. In all cases the flaps were elevated on vessels identified in preoperative review of the CE-MRA. There was a significant difference in the rates of conversion from DIEaP to transverse rectus abdominis myocutaneous (TRAM) flaps in the group who underwent CE-MRA in comparison to historical controls from the previous year (P=0.025). CE-MRA is an effective tool for DIEaP flap planning.


Subject(s)
Epigastric Arteries/anatomy & histology , Mammaplasty/methods , Preoperative Care/methods , Surgical Flaps/blood supply , Adult , Female , Humans , Magnetic Resonance Angiography/methods , Middle Aged , Retrospective Studies , Tissue and Organ Harvesting/methods , Treatment Outcome
6.
J Plast Reconstr Aesthet Surg ; 60(11): 1219-24, 2007.
Article in English | MEDLINE | ID: mdl-17720644

ABSTRACT

BACKGROUND: At long-term follow up we cannot easily differentiate between patients who have undergone free transverse rectus abdominis musculocutaneous (TRAM) flap and deep inferior epigastric artery perforator (DIEP) flap breast reconstruction in terms of subjective functional limitations of daily activities. The aim of this study was to evaluate postoperative outcomes and long-term subjective functional deficit in patients following unilateral free TRAM compared with DIEP flap breast reconstruction. METHODS: Sixty consecutive patients who underwent unilateral autologous breast reconstruction were included in the study, 30 of whom had undergone a DIEP flap, and 30 a free TRAM flap. Surgical and postoperative outcome data were collected and a postal questionnaire was sent to each patient at least 6 months postoperatively consisting of a short functional assessment questionnaire and a Short Form 36 (SF-36) survey. RESULTS: We found no significant difference in postoperative outcomes or in the subjective ability to perform activities of daily living, including work, domestic activities, sports and hobbies, between patients who underwent TRAM flap breast reconstruction and those who underwent a DIEP flap, and no significant difference between the groups for scores on the physical functioning, role-physical, or bodily pain scales of the SF-36. CONCLUSION: We conclude that harvesting of the free TRAM flap results in no significant difference in postoperative outcomes or in the subjective ability to perform activities of daily living compared with the DIEP flap.


Subject(s)
Mammaplasty/methods , Postoperative Complications/prevention & control , Rectus Abdominis/transplantation , Adult , Aged , Epigastric Arteries/surgery , Female , Follow-Up Studies , Humans , Middle Aged , Postoperative Complications/physiopathology , Rectus Abdominis/blood supply , Surgical Flaps/blood supply , Surveys and Questionnaires , Treatment Outcome
9.
Dermatol Online J ; 12(1): 17, 2006 Jan 27.
Article in English | MEDLINE | ID: mdl-16638385

ABSTRACT

We present an unusual case of eccrine porocarcinoma in that diagnosis was delayed for many years after the initial lesion appeared, resulting in relatively large tumor.


Subject(s)
Acrospiroma/pathology , Leg , Sweat Gland Neoplasms/pathology , Acrospiroma/surgery , Aged , Humans , Male , Neoplasm Invasiveness , Sweat Gland Neoplasms/surgery
11.
Sarcoma ; 9(1-2): 21-4, 2005.
Article in English | MEDLINE | ID: mdl-18521412

ABSTRACT

We would like to report on our experience of illustrating our operation notes with pre-, per- and post-operative digital images.

12.
J Wound Care ; 13(8): 344-5, 2004 Sep.
Article in English | MEDLINE | ID: mdl-15469221

ABSTRACT

A patient with a non-healing sacral pressure ulcer underwent exploratory surgery. During the procedure a piece of polyurethane sponge was found to have been left in situ. This unusual case highlights the importance of vigilance at dressing changes.


Subject(s)
Bandages/adverse effects , Foreign Bodies/etiology , Pressure Ulcer/therapy , Aged , Foreign Bodies/surgery , Humans , Lumbosacral Region , Polyurethanes , Surgical Sponges , Vacuum
13.
Br J Plast Surg ; 57(4): 362-5, 2004 Jun.
Article in English | MEDLINE | ID: mdl-15145742

ABSTRACT

Despite their classification as benign, desmoid tumours are difficult to diagnose and manage. They are prone to recurrence and resection can be debilitating. Rarely, synchronous or metachronous multicentric desmoid tumours occur and may require further excision. Therefore, early detection of recurrence and multicentric tumours is vital. We present a case of metachronous desmoid tumours, and review the literature to propose a treatment pathway.


Subject(s)
Fibromatosis, Aggressive/surgery , Muscle Neoplasms/surgery , Neoplasms, Second Primary/surgery , Adult , Buttocks , Humans , Magnetic Resonance Imaging , Male , Neoplasms, Second Primary/diagnosis , Tomography, X-Ray Computed
14.
Br J Plast Surg ; 56(7): 689-91, 2003 Oct.
Article in English | MEDLINE | ID: mdl-12969668

ABSTRACT

Perforator flaps have become popular for autologous free tissue breast reconstruction because they reduce the donor site morbidity. It is possible to apply the this principle to the recipient site. We present our experience of using the perforating vessels from the internal mammary artery and vein as recipient vessels for autologous free tissue breast reconstruction flaps in 21 out of 54 consecutive cases (39%). We discuss the technique and its advantages.


Subject(s)
Mammaplasty/methods , Mammary Arteries/surgery , Anastomosis, Surgical/methods , Female , Humans , Surgical Flaps
17.
Ann R Coll Surg Engl ; 83(6): 376-80, 2001 Nov.
Article in English | MEDLINE | ID: mdl-11777128

ABSTRACT

Airway fires are an uncommon but real and devastating complication of tracheostomy. One such fire in a 31-year-old man is described. Surgical fires are discussed, and 15 reported cases of tracheostomy fire are reviewed. A tracheostomy protocol, adopted by our department and designed to avoid this life-threatening complication, is described. Surgeons and anaesthetists involved in tracheostomy must understand the fire hazard and how to avoid it.


Subject(s)
Electrocoagulation/adverse effects , Fires/prevention & control , Tracheostomy/adverse effects , Adult , Anesthesia, General/methods , Hemostasis, Surgical/adverse effects , Humans , Male , Oxygen/adverse effects
18.
Br J Plast Surg ; 53(5): 427-33, 2000 Jul.
Article in English | MEDLINE | ID: mdl-10876284

ABSTRACT

Recently, there has been significant interest both from government and medical practitioners in the discipline of evidence-based medicine. In this article we discuss the problems faced by the plastic surgeon when trying to ensure that practice is evidence-based and highlight some of the reasons behind these difficulties. With the rapid growth of the Internet we also outline its use to access high quality information for the plastic surgeon.


Subject(s)
Evidence-Based Medicine , Surgery, Plastic , Benchmarking , Humans , Patient Satisfaction , Randomized Controlled Trials as Topic , Research Support as Topic
19.
Article in English | MEDLINE | ID: mdl-9431535

ABSTRACT

This article describes a series of 21 consecutive cases, each involving a solitary median maxillary central incisor; the patients were seen in the Department of Dentistry or the Victorian Clinical Genetics Unit, Murdoch Institute, at the Royal Children's Hospital, Melbourne, from 1966 to 1997. The spectrum of anomalies and associated features present in these cases--solitary median maxillary central incisor, choanal atresia, and holoprosencephaly--is described, and the literature related to the features, including genetic studies in these conditions, is reviewed. We relate our findings in these cases to current knowledge of developmental embryology. It is hoped that the findings, together with our interpretation of them, will help to clarify understanding of solitary median maxillary central incisor syndrome. This syndrome was previously considered a simple midline defect of the dental lamina, but it is now recognized as a possible predictor of holoprosencephalies of varying degrees in the proband, in members of the proband's family, and in the family's descendants.


Subject(s)
Body Height , Choanal Atresia/pathology , Growth Disorders/pathology , Incisor/abnormalities , Nose Diseases/congenital , Choanal Atresia/genetics , Constriction, Pathologic/congenital , Constriction, Pathologic/genetics , Female , Forecasting , Growth Disorders/genetics , Heart Defects, Congenital/pathology , Holoprosencephaly/pathology , Humans , Infant , Intellectual Disability , Male , Maxilla , Nasal Obstruction/congenital , Nose Diseases/genetics , Syndrome
20.
Br J Plast Surg ; 49(7): 497-8, 1996 Oct.
Article in English | MEDLINE | ID: mdl-8983558

ABSTRACT

A case is presented which highlights the importance of long term follow-up and early intervention in this unusual dermatosis. A 39-year-old man presented with an extensive tumour of his left ear and scalp. Surgery was not feasible. The progressive nature of the lesion eventually killed the patient.


Subject(s)
Carcinoma, Squamous Cell/surgery , Ear Neoplasms/pathology , Neoplastic Syndromes, Hereditary/surgery , Skin Neoplasms/surgery , Adult , Carcinoma, Squamous Cell/pathology , Fatal Outcome , Humans , Long-Term Care , Magnetic Resonance Imaging , Male , Neoplastic Syndromes, Hereditary/pathology , Skin Neoplasms/pathology
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