ABSTRACT
NIMROD is the Near and InterMediate Range Order Diffractometer of the ISIS second target station. Its design is optimized for structural studies of disordered materials and liquids on a continuous length scale that extends from the atomic, upward of 30 nm, while maintaining subatomic distance resolution. This capability is achieved by matching a low and wider angle array of high efficiency neutron scintillation detectors to the broad band-pass radiation delivered by a hybrid liquid water and liquid hydrogen neutron moderator assembly. The capabilities of the instrument bridge the gap between conventional small angle neutron scattering and wide angle diffraction through the use of a common calibration procedure for the entire length scale. This allows the instrument to obtain information on nanoscale systems and processes that are quantitatively linked to the local atomic and molecular order of the materials under investigation.
ABSTRACT
alpha 1-antitrypsin phenotypes were determined in cord sera of 1,010 healthy term infants of black, white and Hispanic background, by the crossed immunoelectrophoresis technique of Fagerhol and Laurell. Among the black group, M prevalence (97%) was higher than among the Hispanic group (88%). MS prevalance in the Hispanic group (6.7%) was higher than among black (1.5%) or white (3.9%) infants. Among those with an M pattern a "step" variant representing a shift of the relative amounts of protein in the major peaks of the M pattern, was found in 96% of neonates, but only among 9.8% of infants one months to two years of age and 18% among children two to ten years of age, regardless of race. Quantitative values of alpha 1-antitrypsin were not decreased among MS and MZ infants.
