ABSTRACT
This retrospective study evaluated tear film (TF) interferometry on horses examined in Northern Italy in 2019-2021. The objectives were to evaluate horses affected by keratitis, and to describe TF values in horses with no evidence of ocular disease. All horses received a complete ophthalmic examination and were examined with the Ocular Surface Analyser, Veterinary-setting, prior to eye manipulation, staining and sample collection. Eighteen horses with no evidence of ocular disease were included in the comparison group. Additionally, 46 horses displaying signs of keratitis (neovascularization, corneal opacities, ulceration, epithelial and subepithelial infiltrates) were evaluated. These horses were divided into presumed non-infectious and infectious or presumed infectious keratitis groups (one with proven bacterial origin, and the others with diagnosed or presumptive keratomycosis) with the former including immune-mediated keratitis. From the observations of TF interferometry in the comparison population the authors concluded that for non-invasive break-up time (NIBUT), the estimated preliminary reference interval was 10.4-31.2s, and for tear meniscus height (TMH), it was 0.215-0.457mm. Moreover, within the keratitis population, from an interferometric point of view punctate lesions of the ocular surface were present in all cases of active diagnosed or presumptive subepithelial keratomycosis but not in any of the non-infectious cases, either non-ulcerative or ulcerative. Limitations of the study include a relatively low number of horses examined and the fact that the diagnosis of infectious keratitis was presumptive and based on clinical improvement after treatment in some cases. To the authors' knowledge, this is the first report of TF interferometry performed in horses.
Subject(s)
Corneal Ulcer , Eye Infections, Fungal , Horse Diseases , Keratitis , Animals , Horses , Retrospective Studies , Horse Diseases/drug therapy , Corneal Ulcer/drug therapy , Corneal Ulcer/pathology , Corneal Ulcer/veterinary , Keratitis/pathology , Keratitis/veterinary , Eye Infections, Fungal/epidemiology , Eye Infections, Fungal/pathology , Eye Infections, Fungal/veterinaryABSTRACT
Canine retinal S antigen has been purified to study the retinal progressive atrophy of the dog. The purified antigen will be used to detect, by the ELISA technique, specific autoantibody in dogs with ocular diseases.
Subject(s)
Antigens/isolation & purification , Autoimmune Diseases/veterinary , Dog Diseases/immunology , Retina/pathology , Retinal Degeneration/veterinary , Animals , Antigens/immunology , Arrestin , Atrophy , Autoantibodies/analysis , Dogs , Electrophoresis, Polyacrylamide Gel , Enzyme-Linked Immunosorbent Assay , Male , Rats , Rats, Inbred Lew , Retina/immunology , Retinal Degeneration/immunology , Retinal Diseases/immunology , Retinal Diseases/veterinaryABSTRACT
After an extensive review of the literature showing how the existence of diabetic retinopathy in the dog had been confirmed by various research workers and in particular by histological studies, a clinical picture of this retinopathy is given, together with a description of tis individual features based on opthalmoscopic examinations carried out on 13 dogs with diabetes and illustrated with the photographs taken with the KOWA retinograph.
