Diagnostic performance of fine needle aspiration cytology (FNAC) in the diagnosis of breast lumps.

OBJECTIVE: The aim of the study was to evaluate the diagnostic performance of line needle aspiration cytology in the diagnosis of breast lumps. METHODS: All patients who underwent FNA breast lumps at Rehman Medical Institute, Peshawar during 2006 to 2008 were included in this descriptive cross-sectional study. The FNA procedure was performed & interpreted by experienced cyto-pathologists. FNAC of 102 breast lumps were analysed. RESULTS: The age range of the patients was 15-80 years (mean 38.11 years). Inadequate cases were 2.94%, malignant 30.39%, atypical/suspicious of malignancy 6.86%, and benign 59.80%. Malignant lesions predominated in the 5th and 6th and benign in the 3rd and 4th decades of life. CONCLUSION: FNAC of breast is simple, cost-effective and less traumatic method for diagnosis of breast lumps. Combined with physical examination and imaging studies, it is a highly sensitive diagnostic tool and can reduce the need for open biopsy.

Adenomyosis among samples from hysterectomy due to abnormal uterine bleeding.

BACKGROUND: Adenomyosis is one of the most common, yet under diagnosed, underlying cause of abnormal uterine bleeding. We aimed to evaluate the presence of adenomyosis among the patients who presented with abnormal uterine bleeding. METHODS: This was a retrospective study carried out on hysterectomy specimens of subjects who presented to the gynaecologist with the complaint of abnormal uterine bleeding not responding to conservative treatment. Excluded are the hysterectomies performed for malignant pelvic neoplasms and hysterectomy following labour for postpartum haemorrhage. RESULTS: A total of 861 women underwent hysterectomy out of which 779 w\ere abdominal and 82 vaginal from Jan 2008 to Dec 2012. Adenomyosis was found in 296 of the 861 specimens studied. The most frequent combination of diagnosis was leiomyoma and adenomyosis. Pathologic conditions associated with adenomyosis were: leiomyomas 150 (50.6%), endometrial polyp 16 (5.4%), genital prolapse 12 (4.05%), chronic endometritis 10 (3.3%), endometrial hyperplasia 5 (1.6%), endocervical polyps 2 (0.6%). CONCLUSION: Adenomyosis is a common pathologic finding significantly related to reproductive and menstrual characteristics of the patients.