ABSTRACT
INTRODUCTION: We present a six year study (from 1998-2003 year) concerning Non-Hodgkin's lymphomas originating from the gastrointestinal tract according to the classification of WHO (1997). RESULTS: For the mentioned period in the University Hospital "Sveti Georgi" are diagnosed 22 cases of extranodal Non-Hodgkin's lymphomas of the gastrointestinal tract; 9 (40.9%) of them originated from lymph nodes of Valdier, 1 (4.5%)--from parotid gland, 6 (27.3%)--from stomach, 4 (18.2%) from large intestine and 2 (9.1%) cases from the small intestine. The ratio men/women is equal, and the age is between 20 to 84 years. All the lymphomas were B-cells type; in 6 cases they are MALT lymphomas, and in the rest of the cases--diffuse large cell B-cell type Non-Hodgkin's lymphomas. CONCLUSION: In our investigation all Non-Hodgkin's lymphomas of the gastrointestinal tract are of B-cell type. Obviously their diagnosis is being late; probably because diffuse large cell B-cell type Non-Hodgkin's lymphomas are the predominant type.
Subject(s)
Gastrointestinal Neoplasms/pathology , Lymphoma, B-Cell, Marginal Zone/pathology , Lymphoma, Large B-Cell, Diffuse/pathology , Adult , Aged , Aged, 80 and over , Female , Gastrointestinal Neoplasms/epidemiology , Humans , Lymphoma, B-Cell, Marginal Zone/epidemiology , Lymphoma, Large B-Cell, Diffuse/epidemiology , Male , Middle Aged , Retrospective Studies , Young AdultABSTRACT
Carcinoid tumors originate from the argentofile cells found at the bottom of the crypt of Lieberkuhn. In spite of their slow growth and comparatively better prognosis, the carcinoid are malignant tumors, which effective treatment is their surgical resection. We present 10 patients with carcinoid of the gastrointestinal tract (GIT)--3 from small intestine, 3 from large intestine, 2 from appendix, I from rectum and 1 from stomach, operated at our clinic for a 6 year period of time.
Subject(s)
Carcinoid Tumor , Gastrointestinal Neoplasms , Adult , Aged , Aged, 80 and over , Carcinoid Tumor/epidemiology , Carcinoid Tumor/pathology , Carcinoid Tumor/surgery , Disease-Free Survival , Female , Gastrointestinal Neoplasms/epidemiology , Gastrointestinal Neoplasms/pathology , Gastrointestinal Neoplasms/surgery , Humans , Male , Middle Aged , Neoplasm Invasiveness , Neoplasm MetastasisABSTRACT
A case of a 71-year-old man with dyspnea attacks, weight loss and astheno-adynamia syndrome is presented. A 7.7 x 6.4 cm well-delineated tumor is found intraoperatively in the superior lobe of the left lung towards the posterior mediastinum. The tumor cells resemble hepatocytes histologically and show expression for alpha-fetoprotein. Diagnosis primary hepatoid lung adenocarcinoma is made. Pericellular basal membrane-like material is found on electron microscopy. A clinico-morphological discussion regarding the biological behavior and prognosis of this rare tumor is presented.
Subject(s)
Adenocarcinoma/secondary , Liver Neoplasms/pathology , Lung Neoplasms/secondary , Adenocarcinoma/diagnostic imaging , Adenocarcinoma/surgery , Aged , Hepatocytes/pathology , Humans , Liver Neoplasms/diagnostic imaging , Liver Neoplasms/surgery , Lung Neoplasms/diagnostic imaging , Lung Neoplasms/surgery , Male , Tomography, X-Ray ComputedSubject(s)
Carcinoma, Papillary/diagnosis , Lymph Nodes/pathology , Lymphoma, Non-Hodgkin/diagnosis , Mediastinal Neoplasms/diagnosis , Neoplasms, Multiple Primary/diagnosis , Thyroid Neoplasms/diagnosis , Adult , Carcinoma, Papillary/pathology , Diagnosis, Differential , Fatal Outcome , Humans , Lymphoma, Non-Hodgkin/pathology , Male , Mediastinal Neoplasms/pathology , Neoplasms, Multiple Primary/pathology , Thyroid Neoplasms/pathologyABSTRACT
A case of a 20-year-old woman who developed a hemolytic-uremic syndrome while using the contraceptive drug Rigevidon is reported. Clinically the disease was manifested by acute renal failure, thrombocytopenic purpura and hemolytic anemia. The treatment with antiaggregants, anticoagulants, hemodialysis and plasmapheresis was without effect. The diagnosis was proved by the postmortem examination. The risks of the use of oral contraceptives and the need of new and better methods for contraception are discussed.
Subject(s)
Contraceptives, Oral, Hormonal/adverse effects , Ethinyl Estradiol/adverse effects , Hemolytic-Uremic Syndrome/chemically induced , Norgestrel/adverse effects , Acute Kidney Injury/chemically induced , Acute Kidney Injury/diagnosis , Acute Kidney Injury/pathology , Adult , Ethinyl Estradiol-Norgestrel Combination , Female , Hemolytic-Uremic Syndrome/diagnosis , Hemolytic-Uremic Syndrome/pathology , Humans , Purpura, Thrombocytopenic/chemically induced , Purpura, Thrombocytopenic/diagnosis , Purpura, Thrombocytopenic/pathology , Time FactorsABSTRACT
8136 deceased at the clinics of the Higher Medical Institute "I. P. Pavlov" for the period of 1975-1984 are studied. 265 of the deceased (3.28%) have tumours of the central nervous system (cns), among which astroglial tumours predominate (73.21%), while nonastroglial tumours represent 26.79%. The largest is the number of astrocytomas II degree--99 cases, followed by astrocytomas III degree--47 cases, multiform glioblastomas--28 cases and astrocytomas I degree--20 cases in accordance with differentiation of astroglial tumours. A larger part of astroglial tumours are localized supratentorially (86.6%) as the mature age is manifested mainly (31-60 years)--61.34% (p less than 0.001). The male sex predominates (61.84%) over the female sex (38.16%) (p less than 0.001) among the decreased with astroglial tumours. The cerebral oedema--64.43% is the most frequent immediate cause for the death of these patients. Menigiomas (42.25%) predominate among 71 patients with nonastroglial tumours, followed by meduloblastomas and ependimomas--15.49% and respectively 12.68%, oligodendrogliomas 8.45%. The remaining histogenetic types of papillomas of choroid plexus, angioreticulomas (hemangioblastomas according to the classification the World Health Organization, 1979), craniopharingiomas are more rarely encountered tumours.
