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3.
Rev Med Brux ; 18(4): 187-91, 1997 Sep.
Article in French | MEDLINE | ID: mdl-9411640

ABSTRACT

Hepatitis A is a beginning disease in childhood but sometimes a very dangerous disease in adults. It is necessary to vaccine the non immune "risk groups". Hepatitis B is responsible for two millions deafs every year. Hepatitis B is a sexually transmissible disease. Everybody would be vaccinated.


Subject(s)
Hepatitis A/prevention & control , Hepatitis B Vaccines , Hepatitis B/prevention & control , Viral Hepatitis Vaccines , Adult , Child , Hepatitis A/transmission , Hepatitis A Vaccines , Hepatitis B/mortality , Hepatitis B/transmission , Humans , Immunization Schedule , Risk Factors
4.
Gastroenterol Clin Biol ; 14(5): 423-7, 1990.
Article in French | MEDLINE | ID: mdl-2365174

ABSTRACT

Twenty-four intragastric acidity was measured by continuous recording using intragastric glass electrodes in 16 normal controls, 18 inactive duodenal ulcer patients and 7 patients with atrophic gastritis. Median pH for the 24 h period, for the 8 AM-8 PM period, and for the 8 PM-8 AM period were significantly lower in duodenal ulcer patients than in controls (1.19 vs 1.78; 1.17 vs 2.05; 1.27 vs 1.64). Median pH for these 3 periods were significantly higher in patients with atrophic gastritis than in controls (3.90; 3.72; 3.81). The median pH for the 24 h period was higher than the lower quartile value of the control group in 33 per cent of duodenal ulcer patients. During the night (24 h-3 h), duodenal ulcer patients had significantly lower median pH (1.03) than controls (1.51). Antisecretory treatment should be directed to decrease this period of unbuffered acidity.


Subject(s)
Duodenal Ulcer/physiopathology , Gastritis, Atrophic/physiopathology , Gastritis/physiopathology , Adult , Circadian Rhythm , Gastric Acidity Determination , Gastric Juice/metabolism , Humans , Hydrogen-Ion Concentration , Male , Middle Aged , Monitoring, Physiologic , Smoking , Time Factors
5.
Rev Med Brux ; 10(6): 239-44, 1989 Jun.
Article in French | MEDLINE | ID: mdl-2772461

ABSTRACT

Twenty four hour intragastric acidity was measured by continuous recording using intragastric glass electrodes in 16 controls, 18 inactive duodenal ulcer patients and 7 patients suffering from atrophic gastritis. Medians pH for the 24h period, for the 8 AM-8 PM period, for the 8 AM-8 PM period were significantly lower in duodenal ulcer patients than in controls (1.19 vs 1.78; 1.17 vs 2.05; 1.27 vs 1.64). Median pH for these three periods were significantly higher in patients suffering from atrophic gastritis than in controls (3.90; 3.72; 3.81). In duodenal ulcer patients, 33 p 100 had medians for the 24h period higher than the lower quartile value of the control group. During the night (24h-3h) duodenal ulcer patients had median pH (1.03) significantly lower than controls (1.51). Antisecretory treatment should be directed to decrease this period of unbuffered acidity.


Subject(s)
Duodenal Ulcer/metabolism , Gastric Acid/metabolism , Gastritis, Atrophic/metabolism , Gastritis/metabolism , Adult , Gastric Acidity Determination/methods , Humans , Hydrogen-Ion Concentration , Male , Middle Aged
6.
Gastroenterol Clin Biol ; 12(12): 941-5, 1988 Dec.
Article in French | MEDLINE | ID: mdl-3069551

ABSTRACT

Twenty-four-hour intragastric pH monitoring was performed in 20 patients with duodenal ulcer in order to compare the results obtained with placebo, ranitidine 300 mg and cimetidine 800 mg administered one hour (7 PM) after evening meal (6 PM). During each 24 h period (8 AM-8 AM), gastric pH was continuously monitored in standardized dietary conditions. Treatment was started the evening (7 PM) before the test. Median acidity was calculated and percent of time of recording at or above any pH unit was graphically represented. Median acidity and areas under the curves were submitted to statistical comparison. The values were computed for the 24-h period, for the 8 AM-8 PM period, for the 8 PM-8 AM period. In these three periods studied gastric acidity decreased more with ranitidine than with cimetidine. No statistical difference was found between cimetidine and placebo for the 8 AM-8 PM period.


Subject(s)
Cimetidine/pharmacology , Duodenal Ulcer/drug therapy , Gastric Acid/drug effects , Ranitidine/pharmacology , Adult , Aged , Eating , Female , Gastric Acidity Determination , Humans , Male , Middle Aged , Time Factors
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