Subject(s)
Cimetidine/therapeutic use , Duodenal Ulcer/drug therapy , Guanidines/therapeutic use , Acute Disease , Aged , Humans , MaleABSTRACT
Three patients developed severe, incapacitating diarrhea after antibiotic administration. Presenting features included abdominal discomfort, hematochezia, and hypokalemia from voluminous diarrhea. Roetgenographic studies in 1 patient were normal and proctoscopic examinations in 2 patients failed to show antibiotic-associated colitis. Stool cultures were negative. Despite cessation of antibiotics and symptomatic therapy, the diarrhea continued. After the administration of oral tetracycline, the diarrhea stopped without recurrence even after the tetracycline was discontinued. These clinical results suggest that patients with antibiotic-associated diarrhea may benefit from tetracycline when standard medical therapy fails.
Subject(s)
Anti-Bacterial Agents/adverse effects , Diarrhea/chemically induced , Tetracycline/therapeutic use , Administration, Oral , Aged , Ampicillin/adverse effects , Cephalexin/adverse effects , Cephalothin/adverse effects , Clindamycin/adverse effects , Diarrhea/drug therapy , Female , Gentamicins/adverse effects , Humans , Middle Aged , Neomycin/adverse effects , Tetracycline/administration & dosageSubject(s)
Guanidines/therapeutic use , Imidazoles/therapeutic use , Zollinger-Ellison Syndrome/drug therapy , Administration, Oral , Aged , Gastric Juice/drug effects , Guanidines/administration & dosage , Guanidines/pharmacology , Humans , Imidazoles/administration & dosage , Imidazoles/pharmacology , Injections, Intravenous , Male , Receptors, Histamine H2/drug effects , Secretory Rate/drug effectsABSTRACT
A patient with a leiomyoma of the esophagus is reported because it reached extraordinary size before becoming symptomatic and caused some difficulty in diagnosis despite its large size. Diagnosis was made with the fiberoptic esophagoscope after standard roentgenograms and rigid esophagoscopy were inconclusive. The tumor was removed through a cervical incision. Attention is called to the potential fatal outcome of these lesions.
