One night of partial sleep deprivation affects habituation of hypothalamus and skin conductance responses.

Sleep disturbances are prevalent in clinical anxiety, but it remains unclear whether they are cause and/or consequence of this condition. Fear conditioning constitutes a valid laboratory model for the acquisition of normal and pathological anxiety. To explore the relationship between disturbed sleep and anxiety in more detail, the present study evaluated the effect of partial sleep deprivation (SD) on fear conditioning in healthy individuals. The neural correlates of 1) nonassociative learning and physiological processing and 2) associative learning (differential fear conditioning) were addressed. Measurements entailed simultaneous functional MRI, EEG, skin conductance response (SCR), and pulse recordings. Regarding nonassociative learning, partial SD resulted in a generalized failure to habituate during fear conditioning, as evidenced by reduced habituation of SCR and hypothalamus responses to all stimuli. Furthermore, SCR and hypothalamus activity were correlated, supporting their functional relationship. Regarding associative learning, effects of partial SD on the acquisition of conditioned fear were weaker and did not reach statistical significance. The hypothalamus plays an integral role in the regulation of sleep and autonomic arousal. Thus sleep disturbances may play a causal role in the development of normal and possibly pathological fear by increasing the susceptibility of the sympathetic nervous system to stressful experiences.

A quarter century of the analysis of verbal behavior: an analysis of impact.

The Analysis of Verbal Behavior (TAVB) has been published since 1982, and during this time, interest in verbal behavior research appears to have increased substantially within behavior analysis. The purpose of the present analysis was to assess the influence of TAVB on the field by (a) counting citations of TAVB articles in the Journal of the Experimental Analysis of Behavior (JEAB) and the Journal of Applied Behavior Analysis (JABA) from 1983 through 2007, (b) examining which other journals cite TAVB, and (c) calculating impact-factor estimates for 2003 through 2007. Citations of TAVB articles began to appear in JEAB and JABA in the late 1980s to early 1990s, and by the end of 2007, almost a third of all articles published in TAVB had been cited in either JEAB or JABA. Other journals that cite TAVB include The Behavior Analyst and The Psychological Record. The estimated impact factor ranged from 0.267 to 0.600. Strategies for increasing the impact of TAVB are discussed.