ABSTRACT
The article is devoted to biography of Leonid Grinevetskiy (1853-1892) - a medical officer, alumnus of Imperial military-medical academy, first commander of Anadyr region on Chukotka. The article presents the characteristic of activity of the talented medical researcher, Russian scientist and administrator.
Subject(s)
Military Medicine/history , History, 19th Century , History, 20th Century , Russia (Pre-1917)Subject(s)
Diagnostic Services , Insurance, Health , Laboratories, Hospital , Diagnostic Services/economics , Diagnostic Services/legislation & jurisprudence , Diagnostic Services/organization & administration , Insurance, Health/economics , Insurance, Health/legislation & jurisprudence , Laboratories, Hospital/economics , Laboratories, Hospital/legislation & jurisprudence , Laboratories, Hospital/organization & administration , SiberiaABSTRACT
Immunoregulatory lymphocytes of SD2-, SD4-, SD8- and SD2-phenotypes have been assayed using monoclonal antibodies in peripheral blood of infertile women with external genital endometriosis and tubal-peritoneal infertility. The tested cells did not markedly differ from those in control fertile patients. Serum concentrations of immunoglobulin M were increased in women with endometriosis. Immunoglobulin concentrations widely varied in the peritoneal fluid, with a statistically significant elevation of IgA and IgM in women with tubal-peritoneal infertility.
Subject(s)
Endometriosis/immunology , Immunoglobulins/analysis , Infertility, Female/immunology , Ovarian Neoplasms/immunology , T-Lymphocytes/immunology , Uterine Cervical Neoplasms/immunology , Adult , Endometriosis/complications , Female , Humans , Infertility, Female/etiology , Leukocyte Count , Ovarian Neoplasms/complications , Uterine Cervical Neoplasms/complicationsABSTRACT
Surface-active substances of lung tissue, covering the alveoli, resembled the biological membranes in their structure. Their composition was controlled, among the other factors, also by free radical oxidation reactions. Under conditions of circulatory hypoxia the activity of antioxidative enzymes correlated with the alterations in antioxidative activity, with the rates of spontaneous and inducible lipid peroxidation in lung surfactants. As surfactant exhibited a limited antioxidative activity important for resistance of alveolar pneumocytes, their functions may be controlled by various exogenous antioxidants.
Subject(s)
Lipid Metabolism , Pulmonary Alveoli/metabolism , Pulmonary Surfactants/metabolism , Animals , Dogs , Free Radicals , Hot Temperature , Humans , Lipid Peroxides/metabolism , Microsomes/metabolism , Oxidation-Reduction , Oxygen/pharmacology , Rabbits , Spectrophotometry, Infrared , Vitamin E/pharmacologyABSTRACT
In the purified plasma membranes of rat liver the antiradical protection systems were revealed involving superoxide dismutase, glutathione peroxidase, glutathione reductase, lipid-dependent and water-soluble catalase, and reduced glutathione. Early changes were observed in these systems after total-body X-irradiation (LD50/30). The authors discuss the role of a plasma membrane in the radiation response of cells.