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1.
Int J Clin Pract ; 60(12): 1679-80, 2006 Dec.
Article in English | MEDLINE | ID: mdl-16669837

ABSTRACT

Cat scratch disease (CSD), due to Bartonella henselae, is a self-limited chronic lymphadenopathy. A previously healthy 22-year-old woman presented with a palpable painful swelling in the right submandibular region accompanied by enlarged cervical lymph nodes. A diagnosis of B. henselae infection was made according to her personal history that divulged frequent contacts with cats and to a high titre of immunoglobulin G (IgG) and IgM antibodies for this agent. The patient improved within 1 month without the requirement of antibiotic treatment or surgery. The CSD should always be included in the differential diagnosis of all equivocal masses in the neck, especially in young individuals. In addition, it is important that a meticulous personal history is obtained.


Subject(s)
Cat-Scratch Disease/complications , Edema/etiology , Parotid Diseases/etiology , Adult , Animals , Cats , Female , Humans
2.
Gynecol Endocrinol ; 18(4): 227-32, 2004 Apr.
Article in English | MEDLINE | ID: mdl-15293895

ABSTRACT

Our objective was to investigate the effects of 5-year therapy with tibolone on the lipid profile in postmenopausal women with mild hypercholesterolemia (total cholesterol, 241 +/- 7 mg/dl; LDL cholesterol, 153 +/- 9 mg/dl). Eighty-two patients were divided into two groups. Group A (53 women) received 2.5 mg of tibolone per day. Group B (29 women) received no tibolone. Total, low- and high-density lipoprotein cholesterol and lipoprotein(a) were found to be decreased in the tibolone group, by 17.7%, 32%, 15.5% and 12%, respectively (p < 0.01) throughout the 5-year treatment, while triglycerides showed no significant change. The lipid profile in the control group remained at its initial values. Menopausal symptoms disappeared in the treatment group within the first 5 months, whereas they deteriorated in the control group during the first 2 years. Although a few unwanted side-effects on hormone-dependent tissues were observed (including vaginal spotting in 11.3% and febrile hemorrhagic cystic mastopathy in 3.8%) long-term therapy with tibolone seemed to be well tolerated, and appeared to have a beneficial effect on the levels of serum lipids.


Subject(s)
Estrogen Receptor Modulators/therapeutic use , Hormone Replacement Therapy , Hypercholesterolemia/drug therapy , Norpregnenes/therapeutic use , Cholesterol/blood , Cholesterol, HDL/blood , Cholesterol, LDL/blood , Female , Humans , Hypercholesterolemia/blood , Lipids/blood , Lipoprotein(a)/blood , Longitudinal Studies , Middle Aged , Postmenopause , Treatment Outcome , Triglycerides/blood
3.
Clin Microbiol Infect ; 9(12): 1234-7, 2003 Dec.
Article in English | MEDLINE | ID: mdl-14686990

ABSTRACT

Bacillus cereus is a food-borne pathogen that causes a self-limiting gastroenteritis. We describe the case of a 72-year-old woman admitted to our hospital because of acute abdominal colic pain. Over a 2-day period, her clinical condition deteriorated rapidly, with the appearance of acute abdomen. Computed tomography investigation of the abdomen showed a liver abscess (diameter approximately 3 cm). At laparotomy, the abscess was found to be ruptured to the free peritoneal cavity. The final clinical diagnosis was acute peritonitis due to a ruptured liver abscess. Bacillus cereus was isolated from culture of the pus. Up to now, no case of liver abscess due to this organism has been reported.


Subject(s)
Abdomen, Acute/complications , Bacillus cereus/growth & development , Gram-Positive Bacterial Infections/complications , Liver Abscess/microbiology , Abdomen, Acute/microbiology , Abdomen, Acute/surgery , Aged , Fatal Outcome , Female , Gram-Positive Bacterial Infections/microbiology , Humans , Laparotomy , Liver Abscess/surgery
4.
Int J Clin Pharmacol Res ; 22(3-4): 85-8, 2002.
Article in English | MEDLINE | ID: mdl-12837045

ABSTRACT

In the present study, we investigated the effects of a 6-month treatment with orlistat on body weight and lipid profile in 27 overweight women (mean body mass index [BMI]: 27.5 kg/m2; median age: 38.4 years) with mild hypercholesterolemia (total cholesterol: 225 mg/dl; low-density lipoprotein cholesterol [LDL-C]: 162 mg/dl). Orlistat was administered three times per day in conjunction with a hypocaloric diet After 6 months of treatment, body weight decreased by 17.71% and BMI decreased by 18.54%, whereas there was a significant (p < 0.01) improvement in serum lipid levels (total cholesterol: -25.33% LDL-C: -30.86%, high-density lipoprotein cholesterol: +9.37%, triglycerides: -35.97%). In conclusion, orlistat in combination with a low-energy diet seems to have a beneficial effect on body weight and lipid profile in overweight women with mild hypercholesterolemia.


Subject(s)
Anti-Obesity Agents/therapeutic use , Hypercholesterolemia/drug therapy , Lactones/therapeutic use , Obesity/drug therapy , Adult , Anti-Obesity Agents/administration & dosage , Body Mass Index , Body Weight/drug effects , Cholesterol, LDL/blood , Diet, Reducing , Female , Humans , Hypercholesterolemia/complications , Hypercholesterolemia/diet therapy , Lactones/administration & dosage , Lipoproteins, HDL/blood , Middle Aged , Obesity/complications , Obesity/diet therapy , Orlistat , Treatment Outcome , Triglycerides/blood
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