ABSTRACT
Positive dynamics was observed in clinical picture and laboratory tests with sensitive to flureniside originators of pyelonephritis. No side effects were noted. The results obtained permit regarding flureniside as a drug of choice to be used for etiotropic treatment of patients with pyelonephritis caused by a sensitive to this chemotherapeutic agent microorganisms.
Subject(s)
Anti-Bacterial Agents/pharmacology , Anti-Infective Agents, Urinary/pharmacology , Heterocyclic Compounds/pharmacology , Pyelonephritis/microbiology , Acute Disease , Adolescent , Adult , Aged , Aged, 80 and over , Bacteriuria/microbiology , Bacteriuria/urine , Chronic Disease , Female , Humans , Male , Microbial Sensitivity Tests/statistics & numerical data , Middle Aged , Pyelonephritis/urineABSTRACT
Flurenizide, a new home drug preparation, endowed with antituberculosis activity, was administered to 20 patients with freshly detected pulmonary tuberculosis, in combination with etambutole or rifampycin in a daily dose of 0.6 g. After the above chemotherapy, closure of the cavities, diminution in size and consolidation of the foci as well as infiltrates, dispelling of the symptoms of intoxication, and discontinuance of bacteria discharge were observable in 70.0 percent of the cases. The drug is well tolerated by patients and is not associated with side effects. The results obtained permit recommending flurenizide for use in phthisiopulmonological practice.