ABSTRACT
Parallel studies of a complex of placental proteins (placental lactogen, trophoblastic beta-globulin, etc.) will help more precisely detect placental dysfunction at early stages of gestosis, assess fetal status, and timely start correcting therapy. Solcoseryl therapy of placental dysfunction in gestosis is justified in complex with routine therapeutic methods and advisable in slight and medium-severity gestoses.
Subject(s)
Pre-Eclampsia/blood , Pregnancy Proteins/blood , Actihaemyl/therapeutic use , Female , Humans , Pre-Eclampsia/drug therapy , Pregnancy , Pregnancy Proteins/drug effects , Pregnancy Trimester, Second , Pregnancy Trimester, ThirdSubject(s)
Antigens/analysis , Endometritis/immunology , Leukocytes/immunology , Puerperal Infection/immunology , Adult , Female , Humans , Mastitis/immunology , Pregnancy , SolubilitySubject(s)
Antigens/analysis , Leukocytes/immunology , Oophoritis/immunology , Salpingitis/immunology , Adolescent , Adult , Chronic Disease , Female , Humans , Immunodiffusion , SolubilitySubject(s)
Alpha-Globulins/immunology , Antigens/immunology , Chemotaxis, Leukocyte , Phytohemagglutinins/pharmacology , Pre-Eclampsia/immunology , Pregnancy Proteins/immunology , Pregnancy , Adolescent , Adult , Cell Migration Inhibition , Female , Humans , In Vitro Techniques , Pregnancy Trimester, ThirdSubject(s)
Antigens/analysis , Leukocytes/immunology , Pre-Eclampsia/immunology , Pregnancy , Female , Humans , Immunochemistry , SolubilitySubject(s)
Pre-Eclampsia/immunology , Pregnancy Proteins/analysis , Female , Humans , Pregnancy , Pregnancy Trimester, ThirdSubject(s)
Antigens/analysis , Leukocytes/immunology , Oophoritis/immunology , Salpingitis/immunology , Adult , Chronic Disease , Female , Humans , Immunochemistry , SolubilitySubject(s)
C-Reactive Protein/analysis , Pre-Eclampsia/blood , Female , Humans , Immunodiffusion , Kidney Diseases/blood , Precipitin Tests/methods , PregnancySubject(s)
Beta-Globulins/analysis , Kidney , Pre-Eclampsia/blood , Adult , Female , Humans , Kidney Diseases/blood , PregnancyABSTRACT
Immunochemical analysis showed chorionic alpha1-microglobulin to be immunologically different from chorionic alpha2-microglobulin. Some physico-chemical properties of these proteins were studied, and they were found to differ from one another by a number of parameters.
Subject(s)
Alpha-Globulins/analysis , Chorion/immunology , Placenta/immunology , Chemical Phenomena , Chemistry, Physical , Female , Humans , Immunodiffusion , Immunoelectrophoresis , PregnancyABSTRACT
An organospecific alpha2-globulin of human placenta was identified with the aid of immunochemical analysis. This antigen differed immunologically from the alpha2- and beta1-globulins of pregnancy, alpha-fetoprotein, placental lactogen, and chorionic gonadotropin. High level of the antigen revealed was found in the placental tissue and the amniotic fluid at the early terms of pregnancy, but its concentration sharply decreased by the time of labour.