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Attempts to identify herpes simplex virus DNA in normal and diseased human peripheral nerve.
Sze, C I; Mahalingam, R; Wellish, M; Levy, A S; Wu, E; Pfister, S J; Gilden, D H; Kleinschmidt-DeMasters, B K.
Neurology ; 52(6): 1293-5, 1999 Apr 12.
Article in English | MEDLINE | ID: mdl-10214765

ABSTRACT

PCR analysis of DNA extracted from 31 sections of formalin-fixed sural nerve biopsies did not reveal herpes simplex virus (HSV) DNA. Unlike the presence of HSV DNA sequences in normal human brain, spinal cord, and ganglia, HSV DNA is not present in normal or diseased human distal peripheral nerve.


Subject(s)
DNA, Viral/analysis , Peripheral Nerves/chemistry , Peripheral Nervous System Diseases/metabolism , Simplexvirus/genetics , Adolescent , Adult , Aged , Aged, 80 and over , Female , Humans , Male , Middle Aged
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