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1.
Z Gerontol Geriatr ; 48(7): 608-13, 2015 Oct.
Article in German | MEDLINE | ID: mdl-25957246

ABSTRACT

BACKGROUND: Community-acquired pneumonia (CAP) is still an important and serious disease for elderly and geriatric patients. AIMS: For epidemiological and clinical reasons it is important to collate the frequencies of the various degrees of severity of CAP and to obtain information on the spread and degree of the threat to the various risk groups by CAP. In outpatient treatment a simple to execute prognosis score can be used to objectify the assessment of the clinical status of a patient and to support therapeutic decision-making. For this purpose knowledge of the appropriate instruments should be available to potential users. MATERIAL AND METHODS: Since the 1990s a variety of risk scores for stratification of CAP have been developed and evaluated. This article presents the content and value of the available risk scores whereby the advantages and disadvantages of the individual scores are critically compared. Special emphasis is placed on the importance of the risk scores for geriatric patients. RESULTS: At present the decision about outpatient or inpatient treatment is primarily based on the risk score CRB-65. Criteria for intensive care unit admissions are provided by the modified American Thoracic Society (ATS) set of criteria. Overall, risk scores are less reliable for elderly patients than for younger adults. CONCLUSION: For treatment decisions for the elderly, functional aspects should also be considered in addition to the aspects of risk scores discussed here. In particular, the decision about inpatient admission for elderly, geriatric CAP patients should be made on an individual basis taking the benefit-risk relationship into consideration.


Subject(s)
Community-Acquired Infections/diagnosis , Community-Acquired Infections/epidemiology , Geriatric Assessment/statistics & numerical data , Pneumonia, Bacterial/diagnosis , Pneumonia, Bacterial/epidemiology , Proportional Hazards Models , Aged , Aged, 80 and over , Community-Acquired Infections/classification , Female , Germany/epidemiology , Humans , Incidence , Male , Pneumonia, Bacterial/microbiology , Prevalence , Reproducibility of Results , Risk Assessment/methods , Sensitivity and Specificity , Severity of Illness Index
2.
J Comp Physiol B ; 175(1): 45-55, 2005 Jan.
Article in English | MEDLINE | ID: mdl-15645237

ABSTRACT

The edible dormouse (Glis glis) is a small rodent and an obligate hibernator. Dormice undergo strong fluctuations of reproductive output during years that seem to be timed to coincide with future food supply. This behaviour enables them to avoid producing young that will starve with a high probability due to food shortage, and to increase their lifetime reproductive success. Aims of this study were to elucidate the extent to which feeding ecology in the edible dormouse has an impact on body mass and the fatty acid (FA) pattern of the white adipose tissue (WAT) before and after hibernation, which in turn might influence reproductive status in spring. Dormice show strong seasonal fluctuations of the body mass, which is reduced by one third during hibernation. Body mass and its changes depend on autumnal food availability as well as on the dietary FA pattern. During the pre-hibernation fattening period, dormice eat lipid rich food with a high content of linoleic acid. During hibernation, linoleic acid content is slightly but significantly reduced and body mass loss during winter is negatively correlated with the pre-hibernation linoleic acid content in the WAT. No relation between reproductive status and body mass, body condition or the FAs pattern of the WAT could be detected. However, in a year of high reproduction, dormice commence the shift to seed eating earlier than in a year of low reproduction. These seeds could be either a predictor for future food supply in autumn, or represent a high-energy food compensating high energetic costs of sexual activity in male edible dormice.


Subject(s)
Dietary Fats/metabolism , Fatty Acids/metabolism , Food Deprivation , Hibernation/physiology , Muscidae/physiology , Reproduction , Adaptation, Physiological , Adipose Tissue/chemistry , Animals , Body Mass Index , Diet , Ecology , Fatty Acids/analysis , Female , Male , Seasons , Seeds
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