ABSTRACT
The present article describes the chemical characteristics such as pH of aqueous extract, fluorescence, aqueous and alcoholic extractives, lignans and TLC profile of aqueous extract of Bhuiavli (Phyllanthus niruri).
ABSTRACT
In view of the growing interest in Phyllanthus niruri, it was felt necessary to undertake a study of the growth cycle of the herb along with qualitative phytochemical observation in terms of active principle, its distribution in different parts of the plant and effect of storage and the active principle. The main purpose of the study was to develop guidelines for cultivation of the plant, rich in the active principle.
ABSTRACT
Biological activity of saturated diethers viz. 1-benzyloxy/phenoxy-8-alkoxy and 1-alkoxy-8-benzyloxy-3,7-dimethyl-1, 8-octanes (IIa-IIq) prepared from Geraniol, were studied on three mosquito species and the bug Dysdercus koenigii. These diethers exhibited oviposition deterrent and developmental inhibition activities of greater magnitudes than the compounds based on citronellol reported in Part I of this paper. Some of these new compounds inhibit development of mosquitoes at 0.05 ppm and deter oviposition at 0.05 per cent doses. Tests were extended to field simulated conditions in selected cases.
Subject(s)
Culicidae/growth & development , Insect Vectors/growth & development , Octanes/pharmacology , Oviposition/drug effects , Phenyl Ethers/pharmacology , Terpenes , Acyclic Monoterpenes , Animals , Culicidae/classification , Evaluation Studies as Topic , Female , Insect Vectors/classification , Male , Terpenes/chemistryABSTRACT
New series of compounds starting from common terpenoids (Geraniol, citronellol) have been examined for biological activity on mosquito larvae. Many of these exhibited development disruption on eggs as well larvae. Some also affected adult oviposition behaviour. Developmental disturbances were classified as JH type by inducing typical metamorphosis inhibition in Dysdercus koenigii in the standard Hemipteran JH bioassay. Where indicated simulated field trials were also undertaken. This report describes results of bioevaluation of the citronellol based compounds. The results indicate that these show multifarious activity against mosquitoes but at relatively high doses, suggesting that exploration of further structural variety is needed before truly promising analogues can be obtained.
