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Ann Genet ; 38(3): 168-71, 1995.
Article in French | MEDLINE | ID: mdl-8540689

ABSTRACT

A complex translocation involving chromosome 6, 8 and 9 [t(6;9;8)(p23;q34;q22)] associated with other structural and numerical abnormalities was observed on bone marrow karyotype of a woman suffering with acute myeloblastic leukemia (AML2). Fluorescence in situ hybridization agreed with the conventional cytogenetic interpretation by showing that a part of chromosome 6 short arm was inserted on the rearranged chromosome 9 resulting in the t (6;9) usually encountered in AML.


Subject(s)
Chromosomes, Human, Pair 6 , Chromosomes, Human, Pair 8 , Chromosomes, Human, Pair 9 , In Situ Hybridization, Fluorescence , Leukemia, Myeloid/genetics , Translocation, Genetic , Acute Disease , Female , Gene Rearrangement , Humans , Karyotyping , Middle Aged
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