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1.
The Science behind the Study.
Phimister, Elizabeth G; Hamel, Mary Beth; Morrissey, Stephen; Rubin, Eric.
N Engl J Med ; 386(22): 2138, 2022 06 02.
Article in English | MEDLINE | ID: mdl-35648707

Subject(s)
Biomedical Research , Science , Humans
2.
Targeting Cytotoxic T Cells to Tumor.
Phimister, Elizabeth G; Rubin, Eric J.
N Engl J Med ; 386(22): 2145-2148, 2022 06 02.
Article in English | MEDLINE | ID: mdl-35648710

Subject(s)
Antineoplastic Agents , Neoplasms , T-Lymphocytes, Cytotoxic , Antineoplastic Agents/therapeutic use , Humans , Neoplasms/drug therapy , Neoplasms/therapy , T-Lymphocytes
3.
Nineteen Days in America.
Sacks, Chana A; Ingelfinger, Julie R; Taichman, Darren B; Morrissey, Stephen; Malina, Debra; Phimister, Elizabeth G; Stern, Kathy L; Duff, Ellen M C; Hogan, Joseph W; Rubin, Eric J.
N Engl J Med ; 386(26): 2445-2449, 2022 06 30.
Article in English | MEDLINE | ID: mdl-35675201
4.
Genetic Modification in Pig-to-Human Transplantation.
Phimister, Elizabeth G.
N Engl J Med ; 387(1): 79-82, 2022 07 07.
Article in English | MEDLINE | ID: mdl-35731913

Subject(s)
Animals, Genetically Modified , Gene Editing , Transplantation, Heterologous , Animals , Animals, Genetically Modified/genetics , Gene Editing/methods , Genetic Engineering/methods , Humans , Swine , Transplantation, Heterologous/methods
5.
Disclosure of Genetic Risk Revealed in a Research Study.
Castellanos, Angela; Phimister, Elizabeth G; Stefánsson, Kári; Clayton, Ellen W.
N Engl J Med ; 382(8): 763-765, 2020 Feb 20.
Article in English | MEDLINE | ID: mdl-32074427

Subject(s)
Confidentiality/ethics , Disclosure/ethics , Duty to Warn , Heterozygote , Research Subjects , Data Anonymization , Databases, Genetic , Ethics Committees, Research , Female , Genes, BRCA1 , Genes, BRCA2 , Humans , Mutation
6.
A Look Forward - The Frontiers in Medicine Series.
Caulley, Lisa; Ramaswami, Ramya; Longo, Dan L; Phimister, Elizabeth G; Ingelfinger, Julie R; Ropper, Allan H; Stern, Kathy; Burke, Alison E; Knoper, Kimberly M; Seals, Jeffrey J J; Müller, Daniel C; Drazen, Jeffrey M.
N Engl J Med ; 379(1): 85-86, 2018 07 05.
Article in English | MEDLINE | ID: mdl-29972760

Subject(s)
Medicine
7.
Curating the way to better determinants of genetic risk.
Phimister, Elizabeth G.
N Engl J Med ; 372(23): 2227-8, 2015 Jun 04.
Article in English | MEDLINE | ID: mdl-26014597

Subject(s)
Genetic Predisposition to Disease , Genetic Testing/standards , Genetic Variation , Breast Neoplasms/genetics , Genes, BRCA1 , Genes, BRCA2 , Humans
8.
Clinical decisions: Screening an asymptomatic person for genetic risk--polling results.
Schulte, Joann; Rothaus, Carla S; Adler, Jonathan N; Phimister, Elizabeth G.
N Engl J Med ; 371(20): e30, 2014 Nov 13.
Article in English | MEDLINE | ID: mdl-25390759

Subject(s)
Genetic Predisposition to Disease , Genetic Testing , Genome-Wide Association Study , Humans , Male
9.
Screening for trisomies in circulating DNA.
Greene, Michael F; Phimister, Elizabeth G.
N Engl J Med ; 370(9): 874-5, 2014 Feb 27.
Article in English | MEDLINE | ID: mdl-24571760

Subject(s)
Down Syndrome/diagnosis , Genetic Testing/methods , High-Throughput Nucleotide Sequencing , Prenatal Diagnosis/methods , Trisomy/diagnosis , Chromosomes, Human, Pair 18 , Female , Humans , Pregnancy , Trisomy 18 Syndrome
10.
Realizing genomic medicine.
Phimister, Elizabeth G; Feero, W Gregory; Guttmacher, Alan E.
N Engl J Med ; 366(8): 757-9, 2012 Feb 23.
Article in English | MEDLINE | ID: mdl-22356329

Subject(s)
Child Development Disorders, Pervasive/genetics , Chromosome Aberrations , Intellectual Disability/genetics , Mutation , Sequence Analysis, DNA/methods , Humans
11.
Replicating genotype-phenotype associations.
Chanock, Stephen J; Manolio, Teri; Boehnke, Michael; Boerwinkle, Eric; Hunter, David J; Thomas, Gilles; Hirschhorn, Joel N; Abecasis, Goncalo; Altshuler, David; Bailey-Wilson, Joan E; Brooks, Lisa D; Cardon, Lon R; Daly, Mark; Donnelly, Peter; Fraumeni, Joseph F; Freimer, Nelson B; Gerhard, Daniela S; Gunter, Chris; Guttmacher, Alan E; Guyer, Mark S; Harris, Emily L; Hoh, Josephine; Hoover, Robert; Kong, C Augustine; Merikangas, Kathleen R; Morton, Cynthia C; Palmer, Lyle J; Phimister, Elizabeth G; Rice, John P; Roberts, Jerry; Rotimi, Charles; Tucker, Margaret A; Vogan, Kyle J; Wacholder, Sholom; Wijsman, Ellen M; Winn, Deborah M; Collins, Francis S.
Nature ; 447(7145): 655-60, 2007 Jun 07.
Article in English | MEDLINE | ID: mdl-17554299

Subject(s)
Genetic Predisposition to Disease/genetics , Genome, Human/genetics , Genotype , Haplotypes/genetics , Humans , Peer Review, Research/standards , Phenotype , Polymorphism, Single Nucleotide/genetics , Reproducibility of Results
12.
Genomic cartography--presenting the HapMap.
Phimister, Elizabeth G.
N Engl J Med ; 353(17): 1766-8, 2005 Oct 27.
Article in English | MEDLINE | ID: mdl-16251532

Subject(s)
Chromosome Mapping , Genome, Human , Haplotypes , Polymorphism, Single Nucleotide , Genetic Variation , Humans , Linkage Disequilibrium
13.
A tetraploid twist on the embryonic stem cell.
Phimister, Elizabeth G.
N Engl J Med ; 353(16): 1646-7, 2005 Oct 20.
Article in English | MEDLINE | ID: mdl-16236733

Subject(s)
Cell Fusion , Embryo, Mammalian/cytology , Hybrid Cells/physiology , Nuclear Transfer Techniques , Pluripotent Stem Cells/physiology , Polyploidy , Cell Differentiation , Cell Line , Embryo Research , Epigenesis, Genetic , Humans
14.
Two fillips for human embryonic stem cells.
Phimister, Elizabeth G; Drazen, Jeffrey M.
N Engl J Med ; 350(13): 1351-2, 2004 Mar 25.
Article in English | MEDLINE | ID: mdl-14999090

Subject(s)
Cell Line , Embryo, Mammalian/cytology , Stem Cells , Blastocyst/cytology , Cloning, Organism , Government Regulation , Humans , United States
15.
Medicine and the racial divide.
Phimister, Elizabeth G.
N Engl J Med ; 348(12): 1081-2, 2003 Mar 20.
Article in English | MEDLINE | ID: mdl-12646663

Subject(s)
Genetic Predisposition to Disease/ethnology , Genetics, Population , Racial Groups/genetics , Genetic Diseases, Inborn/ethnology , Genomics , Humans
16.
In search of a better HIV vaccine - the heat is on.
Phimister, Elizabeth G.
N Engl J Med ; 348(7): 643-4, 2003 Feb 13.
Article in English | MEDLINE | ID: mdl-12584375

Subject(s)
AIDS Vaccines , HIV Antibodies/metabolism , HIV Envelope Protein gp120/metabolism , HIV-1/immunology , CD4 Antigens/metabolism , Epitopes/metabolism , HIV-1/metabolism , Protein Binding
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