1.
Tex Dent J
; 128(7): 650-1, 656-7, 2011 Jul.
Article
in English
| MEDLINE
| ID: mdl-21928742
Subject(s)
Gingival Diseases/pathology , Gingival Neoplasms/pathology , Neurofibroma/pathology , Child , Diagnosis, Differential , Female , Gingival Diseases/diagnostic imaging , Gingival Diseases/surgery , Gingival Neoplasms/diagnostic imaging , Gingival Neoplasms/surgery , Humans , Maxilla , Neurofibroma/diagnostic imaging , Neurofibroma/surgery , Radiography
2.
J Med Chem
; 52(24): 7966-9, 2009 Dec 24.
Article
in English
| MEDLINE
| ID: mdl-19950927
ABSTRACT
Conformationally constrained mimetics of the laminin cell-adhesion site, YIGSR, are described. The site is the natural antagonist of the integrin-associated laminin receptor 1 (LAMR1) known to mediate metastatic tumor adhesion. The attachment of selected metastatic cell lines toward the constrained antagonists has been assessed. Observed differential responses prompted by folding preferences of the mimetics revealed stronger attachment activities for turnlike structures. The results permit the conformational design of antimetastatic disintegrins.
