1.
Pediatr Blood Cancer
; 60(2): 340-1, 2013 Feb.
Article
in English
| MEDLINE
| ID: mdl-23129570
Subject(s)
Anticonvulsants/adverse effects , Antineoplastic Agents/adverse effects , Methotrexate/adverse effects , Piracetam/analogs & derivatives , Precursor Cell Lymphoblastic Leukemia-Lymphoma/drug therapy , Seizures/drug therapy , Adolescent , Anticonvulsants/administration & dosage , Antineoplastic Agents/administration & dosage , Drug Interactions , Drug Therapy, Combination/adverse effects , Humans , Levetiracetam , Male , Methotrexate/administration & dosage , Piracetam/administration & dosage , Piracetam/adverse effects , Precursor Cell Lymphoblastic Leukemia-Lymphoma/complications , Seizures/etiology
2.
Mycoses
; 56(3): 236-40, 2013 May.
Article
in English
| MEDLINE
| ID: mdl-23020159
ABSTRACT
Mucormycosis has emerged as an increasingly important infection in oncology centres with high mortality, especially in severely immunocompromised patients. We carried out a retrospective study of 11 children with mucormycosis treated in seven French oncology-haematology paediatric wards during the period from 1991 to 2011. Lichtheimia corymbifera and Mucor spp. were the predominant pathogens. Treatment regimens included antifungal therapy, reversal of underlying predisposing risk factors and surgical debridement. Although mucormycosis is associated with high mortality, this infection could be cured in eight of our cases of severely immunocompromised paediatric cancer patients.