[The antagonistic activity of the eubiotic Maxilin towards wound infection and its effect on the antibiotic resistance of microorganisms]. / Antagonisticheskaia aktivnost' éubiotika Maksilin k ranevoi infektsii i ego vliianie na rezistentnost' mikroorganizmov k antibiotikam.

Antagonistic activity of lactic acid bacteria of strain N 2585 of "Maxilin" probiotic in respect to the strains S. aureus, P. aeruginosa, E. coli, Candida albicans and their effect on the level of sustainability of the antibiotic resistant strains S. aureus, E. coli, P. aeruginosa, which are extracted from the patients with open fractures of the mandible under various course of wound process, have been studied. The studies showed that lactic acid bacteria have suppressed growth of strains Candida most actively, followed by P. aeruginosa, S. aureus and E. coli. The use of "Maxilin" probiotic allowed reducing the epidemiological significance of pathogenetic strains already in 3 to 4 days. The sensibility studies showed high activity of the lactic acid bacteria in reducing antibiotic resistance of the strains investigated. It was revealed that "Maxilin" probiotic affects Ps. aeruginosa effectively, somewhat less St. aureus and E. coli. The extracted strains demonstrated sensibility to all investigated antibiotics already in 3 to 4 days.

[Vitamin and health status of miners of the Karaganda coal basin]. / Vitaminnyi status i sostoianie zdorov'ia gorniakov Karagandinskogo ugol'nogo basseina.

Vitamin status, health statistics and capacity for work of miners of Karagandinsky coal field were studied. It was shown that inadequate vitamin nutrition of miners in combination with harmful occupational and environmental factors negatively influence the miner's health status and capacity for work.

[Polyvitaminization--an effective method of optimizing the vitamin status of children]. / Polivitaminizatsiia--éffektivnyi put' optimizatsii vitamminogo statusa detei.

Insufficient vitamin value of the food rations for children at nurseries is expressed in lowered levels of vitamins and their metabolites in the urine, as well as in a higher frequency of vitamin and, particularly, polyvitamin deficiency in children, especially, in the winter-spring period. Improvement of the quality and increasing the quantity of food, prophylactic administration of polyvitamins in the periods of higher vitamin deficiency would be effective and real ways for optimization of vitamin status of children. Dragee "Undevitum" and "Hexavitum" proved to be most effective among the prophylactic polyvitamins, the synergy of action of their components provides the improvement in the values of renal excretion of vitamins and their metabolites, as well as reduction in the frequency of micro-symptoms of polyvitamin deficiency.

[The mechanism of the effect of reserpine on endocrine system function]. / K mekhanizmu vliianiia rezerpina na sostoianie éndokrinnoi sistemy.

The experiments in rabbits and guinea-pigs showed that the use of reserpine, 0.1 and 0.25 mg/kg body weight a day, led to a 2-2.8-fold increase in thyroid hormones and 25-45% enhancement in cortisol in the blood. At the same time cAMP concentrations increased by 87% and almost by 5 times in the thyroid and adrenals, respectively. The pancreas exhibited a 5-fold increase in cAMP, 2.5- and 2.3-fold decrease in insulin in rabbit peripheral blood and in the activity of pancreatic aldolase and dehydrogenases, respectively. Blood levels of glucose reduced by 15-17%.

[Vitamin levels in workers in the main departments of the coke-processing industry]. / Obespechennost' vitaminami rabochikh osnovnykh tsekhov kokso- khimicheskogo proizvodstva.

Providing with vitamins was studied in workers of the main shops of coal-tar chemical industry at the Karaganda Metallurgic Plant. Insufficient providing of workers with vitamins A, C, P and B was recorded. The results of the study have necessitated measures aimed at correcting vitamin-deficiency among these workers with due account for the data obtained.

[The effect of qualitatively different fatty components of the diet on mitochondrial membranes in animals with experimental anthracosis]. / Vliianie kachestvenno razlichnogo zhirovogo komponenta ratsiona na membrany mitokhondrii u zhivotnykh s model'iu antrakoza.

The diets with qualitatively different content of fat were found to produce structural and functional alternations in liver mitochondria of rats with experimental anthracosis. It was established in particular that the increase of the vegetable oil quota in the diet of rats affected the structure and function of mitochondria whereas the diet whose fat component included butter, lard, sunflower oil, and margarine at a ratio of 1:1, 5:1:0.5 reduced the untoward effect of coal dust and exercise on the mitochondrial membranes.

[Energy requirements of miners engaged in open-pit coal mining]. / Energopotrebnost' gorniakov, zaniatykh dobychei uglia otkrytym sposobom.

It has been found that according to the value of daily energy consumption the coal miners engaged in open-cast mining should be referred to group III-IV of work intensity. The determining component of daily energy consumption is energy consumption during the working period the value of which depends on the character of working activity and duration of the working shift. The method of strict evaluation of the calorific value of the food taken and the control of body mass is acceptable for the assessment of daily energy consumption.

[Liver and blood enzyme spectra of rats with model anthracosis based on feeding a diet with additional amounts of methionine and pyridoxine]. / Fermentnye spektry pecheni i krovi krys s model'iu antrakoza na fone vvedeniia v ikh ratsion dopolnitel'nykh kolichestv metionina i piridoksina.

The data obtained during studies of the enzymic spectrum of the liver and blood of rats with experimental anthracosis fed the diet containing additional quota of methionine and pyridoxine are presented. It was established that introduction of additional quota of methionine and pyridoxine in the animals' diet with an optimal fat content reduced the negative manifestations on the part of the enzymic systems of the liver and blood characteristic of experimental anthracosis and thus promoted retardation of fibrous process in the lungs. Additional introduction into the diet of rats with experimental anthracosis of methionine alone appeared ineffective.

[Energy requirement of miners working in modern, highly mechanized coal mines]. / Energeticheskaia potrebnost' gorniakov sovremennykh vysokomekhanizirovannykh ugol'nykh shakht.

It was established that under the conditions of modern highly mechanized coal mines, the miners' work refers mainly to the category of hard and particularly hard physical work. The data of energy losses obtained by indirect calorimetry and accurate calculation of the caloric value of the food taken and control of the body weight were found to be similar.

[Vitamin supply of miners employed in modern highly-mechanized coal mines]. / Vitaminnaia obespechennost' shakhterov sovremennykh vysokomekhanizirovannykh ugol'nykh shakht.

The author studied vitamin C, B2, B6, E, A and carotinoid supply of the miners of modern highly mechanized coal mines. The reduction in the supply of the miners with individual vitamins and frequent manifestations of the microsymptoms of their deficiency were of the microsymptoms of their deficiency were linked to a definite degree with high physiological requirements of the miners, associated with the specificity of work at highly mechanized mines.

[Effect of methionine, retinol, tocopherol and pyridoxine on fibrogenesis in the lungs and vitamin metabolism in rats in an anthracosis model]. / Vliianie metionina, retinola, tokoferola i piridoksina na fibrogenez v legkikh i metabolizm vitaminov u krys s model'iu antrakoza.

It has been discovered in rat experiments that the diet containing an additional amount of methionine and pyridoxine and optimal quantity of fat favoured to a certain degree the retardation of the development of pulmonary fibrosis and reduced the disorders in metabolism of vitamins, characteristic for animals with experimental anthracosis. On the contrary, introduction of an additional amount of retinol into the above complex aggravated the development of pulmonary fibrosis and alterations in vitamin metabolism. At the same time the negative manifestations seen in the animals with experimental anthracosis were removed to a certain measure by administering additional doses of vitamin E.