Fear of Re-Injury, Psychological Factors, and Sport Played Have Negative Impact on Return to Sport Following Medial Patellofemoral Ligament Reconstruction for Patellar Instability.

PURPOSE: To analyze factors that affect return to sport after medial patellofemoral ligament reconstruction (MPFLR), such as psychological factors, sport played, and a positive apprehension test following surgery, and to determine the average return to sport rates and time to return to sport. METHODS: A literature search was conducted according to PRISMA guidelines. Included studies met the following criteria: patients underwent MPFLR for patellar instability, return to sport was recorded, and a factor that affected return to sport was mentioned. Search terms included medial patellofemoral ligament, tibial tubercle osteotomy, tibial tubercle transfer, return to play, and return to sport. RESULTS: 18 of 632 identified studies met inclusion criteria. 1,072 patients that underwent MFPLR were recorded. Return to sport rates and mean/median time ranged from 60.0-100% and 3-10.4 months, respectively. 55.6-84.0% of patients returned to sport without decreasing level of competition. Six of 12 studies (50.0%) reported fear of re-injury as the top reason for patients not returning or returning at a lower level of sport. Volleyball/handball had the lowest return to the same level following surgery (18.2-50.0%). CONCLUSION: Athletes that underwent MPFLR following recurrent patellar instability returned to sport at a range of 60.0-100%. Return to sport at the same level or higher was found to have a lower maximum rate at 55.6-84.0%. Fear of re-injury and sport played were found to have a substantial impact on ability to return to sport. Surgeons can use this information to advise patients on expectations following surgery. LEVEL OF EVIDENCE: IV, systematic review of level III and IV studies.

A Systematic Review to Assess the Relationship between Disseminated Cerebral Aspergillosis, Leukemias and Lymphomas, and Their Respective Therapeutics.

Disseminated disease following invasive pulmonary aspergillosis (IPA) remains a significant contributor to mortality amongst patients with hematologic malignancies (HMs). At the highest risk of mortality are those with disseminated disease to the central nervous system, known as cerebral aspergillosis (CA). However, little is known about the risk factors contributing to disease amongst HM patients. A systematic review using PRISMA guidelines was undertaken to define HM patient subgroups, preventative measures, therapeutic interventions, and outcomes of patients with disseminated CA following IPA. The review resulted in the identification of 761 records, of which 596 articles were screened, with the final inclusion of 47 studies and 76 total patients. From included articles, the proportion of CA was assessed amongst HM patient subgroups. Further, pre-and post-infection characteristics, fungal species, and mortality were evaluated for the total population included and HM patient subgroups. Patients with acute myeloid leukemia and acute lymphoid lymphoma, patients receiving corticosteroids as a part of their HM therapeutic regimen, and anti-fungal prophylaxis constitute the top identified patient populations at risk for disseminated CA. Overall, information presented here indicates that measures for the prevention of IPA should be taken in higher-risk HM patient subgroups. Specifically, the type of anti-fungal therapy used should be carefully considered for those patients with IPA and increased risk for cerebral dissemination. Additional reports detailing patient characteristics are needed to define further the risk of developing disseminated CA from IPA in patients with HMs.

Mediterranean diet adherence, gut microbiota, and Alzheimer's or Parkinson's disease risk: A systematic review.

Alzheimer's disease (AD) and Parkinson's disease (PD) are the two most prevalent neurodegenerative diseases, both without prevention or cure. The Mediterranean diet (MeDi) may be neuroprotective by modulating gut microbiota. We aimed to assess the effects of adherence to MeDi on the gut microbiota in relation to AD or PD risk. A search from inception to November 2020 was conducted in PubMed, CINAHL, EMBASE, Web of Science, Global Health, Biological Abstracts, and Grey Literature Report databases. Two searches were conducted: 1) (MeDi or Microbiota) and (PD or AD) and 2) MeDi and microbiota. Inclusion criteria for papers were specified prior to review. Of 4672 studies identified, 64 were eligible for inclusion. These studies were divided into five groups: MeDi and AD risk (n = 4), MeDi and PD risk (n = 2), MeDi and microbial composition or metabolomics (n = 21), AD and microbial composition or metabolomics (n = 7), and PD and microbial composition or metabolomics (n = 30). Adherence to the MeDi was associated with a lower risk of AD and PD development. Eight genera and two species of bacteria had an inverse relationship with MeDi and AD, and one family, eight genera and three species of bacteria had an inverse relationship with MeDi and PD. More studies are needed to investigate if MeDi, gut microbiota, and neurodegeneration are causally related.

The south american context of diagnostic disclosure of adolescents infected by HIV/AIDS: a systematic literature review.

OBJECTIVE: To analyze the scientific evidence on the disclosure of the diagnostic of adolescents infected by HIV/AIDS in the South American context. DATABASE: Systematic literature review using the PubMed, Cinahal, Embase, Cochrane, BVS, and Global Health databases and the descriptors: adolescent and HIV and family and Argentina or Bolivia or Brasil or Chile or Colombia or Ecuador or French Guiana or Paraguay or Peru or Uruguay or Venezuela. DATA SYNTHESIS: Brasil was the country highlighted. It was verified that parents have a direct and indirect influence over the adolescents' life, especially regarding behaviors and health care. Dialog among family members can reduce adolescents' vulnerability to HIV and encourage diagnostic disclosure. CONCLUSION: It is necessary to amplify research involving adolescents with HIV/AIDS and their parents/caregivers and family members to improve care and reduce the cases of the disease. It is suggested that policies of prevention and treatment should involve families, caregivers, partners, and the community.

The south american context of diagnostic disclosure of adolescents infected by HIV/AIDS: a systematic literature review

SUMMARY OBJECTIVE To analyze the scientific evidence on the disclosure of the diagnostic of adolescents infected by HIV/AIDS in the South American context. DATABASE Systematic literature review using the PubMed, Cinahal, Embase, Cochrane, BVS, and Global Health databases and the descriptors: adolescent and HIV and family and Argentina or Bolivia or Brasil or Chile or Colombia or Ecuador or French Guiana or Paraguay or Peru or Uruguay or Venezuela. DATA SYNTHESIS Brasil was the country highlighted. It was verified that parents have a direct and indirect influence over the adolescents' life, especially regarding behaviors and health care. Dialog among family members can reduce adolescents' vulnerability to HIV and encourage diagnostic disclosure. CONCLUSION It is necessary to amplify research involving adolescents with HIV/AIDS and their parents/caregivers and family members to improve care and reduce the cases of the disease. It is suggested that policies of prevention and treatment should involve families, caregivers, partners, and the community.

RESUMO OBJETIVO Analisar as evidências científicas acerca da revelação diagnóstica de adolescentes infectados pelo HIV/aids no contexto sul-americano. FONTES DE DADOS Revisão sistemática da literatura nas bases de dados PubMed, Cinahal, Embase, Cochrane, BVS e Global Health, utilizando os descritores adolescent and HIV and family and Argentina or Bolivia or Brasil or Chile or Colombia or Equador or French Guiana or Paraguay or Peru or Uruguay or Venezuela. SÍNTESE DOS DADOS O Brasil foi o país de destaque. Verificou-se que os pais exercem influência direta e indireta sobre a vida dos adolescentes, especialmente com relação aos comportamentos e cuidados de saúde. O diálogo entre os membros da família pode reduzir a vulnerabilidade dos adolescentes ao HIV e encorajar a revelação do diagnóstico. CONCLUSÃO É necessário ampliar a pesquisa envolvendo adolescentes, pais/cuidadores, famílias com HIV/aids para melhorar os cuidados e reduzir os casos da doença. Sugere-se que as políticas de prevenção e tratamento envolvam famílias, cuidadores, parceiros e comunidades.

Adding Value by Working with Sponsored Projects.

This case study describes how librarians at Rudolph Matas Library of the Health Sciences at Tulane University have partnered and worked with several departments that fall under the Vice President of Research. Examples include detailed literature searches, cooperative purchasing, and clinical trial registration. Some upcoming activities and opportunities for collaboration will also be discussed. Finally, the authors will share some valuable lessons learned through the process of collaboration with the research infrastructure of the university.

Resource format preferences across the medical curriculum.

OBJECTIVE: This research study sought to determine the formats (print or electronic) of articles and book chapters most-preferred by first-year medical students, third-year medical students entering clinical clerkships, and incoming residents and to determine if these preferences change during the course of the medical curriculum. These trends will enable academic health sciences libraries to make appropriate collection development decisions to best cater to their user populations. METHODS: First-year medical students, third-year medical students, and incoming medical residents were asked to complete a paper survey from September 2014 to June 2015. The survey consisted of five multiple-choice questions, with two questions given space for optional short answers. Quantitative and qualitative responses were collected and calculated using Microsoft Excel. RESULTS: First-year students, third-year students, and incoming residents all preferred to read journal articles and book chapters in print, except in cases where the article or book chapter is under ten pages in length. Although print is preferred, demand for electronic articles and book chapters increases as students progress from undergraduate medical education into residency. The only category where a majority of incoming residents chose an electronic resource was which format they would give to a colleague, if the article or book chapter was critical to the care of an individual patient. CONCLUSIONS: The preference for print resources is strong across the medical curriculum, although residents show an increased preference for electronic materials when compared to first- and third-year students. Academic health sciences libraries should take these preferences into account when making decisions regarding collection development.

A global snapshot of the state of digital collections in the health sciences, 2013.

Two hundred twenty-nine health sciences libraries (HSLs) worldwide were surveyed regarding the availability of digital collections, evidence of the type of digital collections, level of access, software used, and HSL type. Of the surveyed libraries, 69% (n = 157) had digital collections, with an average of 1,531 items in each collection; 49% (n = 112) also had institutional repositories. In most cases (n = 147), these collections were publicly available. The predominant platforms for disseminating these digital collections were CONTENTdm and library web pages. Only 50% (n = 77) of these collections were managed by the health sciences library itself.