ABSTRACT
: Since the introduction of HMG-CoA reductase inhibitors, also known as statins, as an adjunct to diet in the treatment of hyperlipidemia and the greater emphasis placed on reducing low-density lipoprotein (LDL) cholesterol levels in the prevention of atherosclerosis and cardiovascular disease (CVD), there has been less focus on the value of lowering serum triglyceride levels. Many patients are aware of their "good" and "bad" cholesterol levels, but they may not be aware of their triglyceride level or of the association between high triglycerides and the development of CVD. In recent years, however, in light of the increasing incidences of obesity, insulin resistance, and type 2 diabetes, lowering triglyceride levels has gained renewed interest. In addition to the focus on lowering LDL cholesterol levels in CVD prevention, clinicians need to be aware of the role of triglycerides-their contribution to CVD, and the causes and treatment of hypertriglyceridemia.
Subject(s)
Cardiovascular Diseases/etiology , Cardiovascular Diseases/prevention & control , Hypertriglyceridemia/complications , Hypertriglyceridemia/prevention & control , Triglycerides/blood , HumansABSTRACT
Male hypogonadism is increasing in prevalence, particularly in the older male population. Signs and symptoms associated with hypogonadism are often nonspecific and may be difficult to categorize. This article discusses parameters for screening patients at risk, reviews how to establish the diagnosis of primary or secondary male hypogonadism, and offers important considerations for treatment of patients with hypogonadism.
Subject(s)
Hypogonadism , Primary Health Care , Humans , Hypogonadism/diagnosis , Hypogonadism/therapy , Male , Prevalence , TestosteroneABSTRACT
Hypertension, if not appropriately treated, can lead to stroke, kidney failure, myocardial infarction, and death. Substantial evidence from multiple randomized clinical trials demonstrates the benefit of antihypertensive therapy. Healthcare providers seek scientific evidence by which to base treatments. The purpose of this article is to discuss current hypertension guidelines.