ABSTRACT
No disponible
Subject(s)
Humans , Sunlight/adverse effects , Skin Neoplasms/prevention & control , Health Promotion/methods , Health Behavior , Bathing Beaches , AwarenessSubject(s)
Age Distribution , Bathing Beaches/statistics & numerical data , Hot Temperature , Sunbathing/statistics & numerical data , Time Factors , Adolescent , Adult , Chi-Square Distribution , Cross-Sectional Studies , Humans , Middle Aged , Population Surveillance/methods , Reference Values , Seasons , Ultraviolet Rays , Young AdultSubject(s)
Sunbathing , Adolescent , Adult , Bathing Beaches , Cross-Sectional Studies , Female , Health Behavior , Humans , Male , Portugal , Risk Factors , Skin Neoplasms/etiology , Young AdultSubject(s)
Environmental Exposure , Health Behavior , Health Personnel , Self Care , Skin Neoplasms , Sunlight , Adult , Cross-Sectional Studies , Female , Humans , Knowledge , MaleABSTRACT
AIM: To review the dinical and histological data of 20 cases of dermatofibrosarcoma protuberans presenting at two dermatology centres in Lisbon from 1978 to 1998. PATIENTS AND METHODS: The 20 subjects comprised nine males and 11 females ranging in age from 25 to 79 years, with highest frequency of subjects in the 30-50 year olds. We reviewed the clinical features, histopathological aspects, including morphologic variants and immunohistochemical studies. RESULTS: Median age at diagnosis was 51 years and the trunk was the most frequent location. The characteristic histologic storiform pattern was seen in all cases. Three subjects presented fibrosarcomatous areas, one with myoid differentiation and another with multinucleated giant cells. Immunohistochemical stains revealed CD34 expression in the 18 specimens tested, FXIIIa was negative, and these two antigens proved important for the differential diagnosis of this neoplasm. Local wide excision was performed in 13 cases and seven patients underwent Moh's micrographic surgery. Follow-up ranged from 2 months to 17 years and three recurrences were recorded, two following classical surgery and one after Moh's surgery; there was no difference in the rate of local recurrence (15%) for the two kinds of treatment in our series.
Subject(s)
Dermatofibrosarcoma/pathology , Skin Neoplasms/pathology , Adult , Aged , Dermatofibrosarcoma/classification , Dermatofibrosarcoma/surgery , Female , Humans , Male , Middle Aged , Skin Neoplasms/classification , Skin Neoplasms/surgery , Treatment OutcomeSubject(s)
Balneology , Mineral Waters/therapeutic use , Balneology/trends , Baths , Health Resorts , Humans , PortugalABSTRACT
Careful mapping and staining are important steps in securing high quality specimen slides for microscopic examination. We hope that our experiences will be of help to those individuals performing Mohs microscopically controlled surgery.
