ABSTRACT
The traditional Mediterranean diet (MedDiet) is a well-known dietary pattern associated with longevity and improvement of life quality as it reduces the risk of the most common chronic pathologies, such as cancer and cardiovascular diseases (CVDs), that represent the principal cause of death worldwide. One of the most characteristic foods of MedDiet is olive oil, a very complex matrix, which constitutes the main source of fats and is used in the preparation of foods, both raw as an ingredient in recipes, and in cooking. Similarly, strawberries and raspberries are tasty and powerful foods which are commonly consumed in the Mediterranean area in fresh and processed forms and have attracted the scientific and consumer attention worldwide for their beneficial properties for human health. Besides olive oil and berries, honey has lately been introduced in the MedDiet thanks to its relevant nutritional, phytochemical and antioxidant profile. It is a sweet substance that has recently been classified as a functional food. The aim of this review is to present and discuss the recent evidence, obtained from in vitro, in vivo and epidemiological studies, on the potential roles exerted by these foods in the prevention and progression of different types of cancer and CVDs.
Subject(s)
Diet, Mediterranean , Fruit , Functional Food/analysis , Honey , Olive Oil/administration & dosage , Animals , Cardiovascular Diseases/prevention & control , Disease Models, Animal , Humans , Longevity , Neoplasms/prevention & control , Randomized Controlled Trials as TopicABSTRACT
The homogeneous catalytic oxidation of atrazine and fenitrothion in single compound-containing solutions and in mixture, in pure water, was investigated in dark and light-driven oxidation systems using H(2)O(2) as the oxidant and Fe(II) as the catalyst. It was shown that the degradation during the dark Fenton reactions takes place during the first 2h and further prolongation of the reaction time does not lead to enhanced removals. The same holds true for the light-driven reactions. With the photo-Fenton reaction, fenitrothion was completely mineralized while the TOC contained in the atrazine solution was removed by 57%. Both compounds in their parent form were completely eliminated from the first 5 min of the oxidation both when being in the single-containing solutions and in their binary mixture. The oxidation of the TOC in the atrazine solution follows a two-stage second-order kinetic behavior which is attributed to the complex reaction pathways occurring during the oxidation while that of the TOC in the fenitrothion solutions follows a pseudo-first order degradation kinetic and that of binary mixture a two-stage degradation kinetics. The results obtained in this study, clearly indicate that the light-driven Fenton oxidation can be very efficient for the removal of atrazine and especially fenitrothion from polluted waters.
Subject(s)
Atrazine/chemistry , Fenitrothion/chemistry , Kinetics , Oxidation-Reduction , Solutions/chemistryABSTRACT
Propósito: A partir de 1999, la evidencia disponible recomienda un cambio en el enfoque de lostratamientos. Nuestro propósito es describir las características de los tumores de cérvix tratados enGuipúzcoa durante 1998 y analizar las diferencias en los tratamientos entre 1998 y 2002 en los tumoresinvasivos.Material y métodos: La identificación de los casos se realizó a partir de los Registros de TumoresHospitalarios (RTH) y en su defecto de los Archivos del Servicio de Anatomía Patológica yAltas Hospitalarias. La recogida de información fue a partir de los RTH y RCPG (Registro de CáncerPoblacional de Guipúzcoa) y mediante revisión de historias clínicas para las variables no incluídas endichos registros.Resultados: En 1998 en Guipúzcoa se trataron 91 casos. El número de tumores invasivos diagnosticadosen residentes en Guipúzcoa fue de 25 en 1998 y 20 en 2002. En 1998 la clasificación porestadios de la totalidad de tumores tratados en Guipúzcoa fue: estadio 0, 41.8%; estadio I, 17.7%; estadioII, 17,6%; estadio III, 18,7%; y estadio IV, 4.4. La proporción de tumores tratados con radioterapiay quimioterapia con o sin cirugía en estadios II, III y IV aumenta significativamente del año 1998al 2002: 21.4% versus 72.7%; p=0.01.Conclusiones: Entre 1998 y 2002 el tratamiento del cáncer de cérvix invasivo cambia significativamenteadecuándose a la evidencia científica disponible
Purpose: Beginning in 1999, the available evidence recommended a change of focus in thetreatment of cervical cancer. We describe cervical tumours treated in Guipúzcoa during 1998 andanalyse the differences in the treatment of invasive tumours between 1998 and 2002.Material and methods: Cases were identified from the Hospital Tumour Registries (HTR)and, where not available, from the Archives of the Anatomic Pathology Service and HospitalDischarges. Information was collected from the HTR and the Guipúzcoa Population Cancer Registryand by review of clinical records for variables not included in these registries.Results: Ninety-one cases of cervical carcinoma diagnosed and/or treated in Guipúzcoa in 1998were included. The number of invasive tumours diagnosed in residents of Guipúzcoa was 25 in 1998and 20 in 2002. In 1998 the classification by stage of all such tumours treated in Guipúzcoa was: stage0, 41.8%; stage I, 17.7%; stage II, 17.6%; stage III, 18.7%; and stage IV, 4.4%. The proportion oftumours treated with radiation therapy and chemotherapy with or without surgery in stages II, III andIV increased significantly from 1998 to 2002: 21.4% versus 72.7%; p=0.01.Conclusion: Between 1998 and 2002 the treatment of invasive cervical cancer in Guipúzcoa changed significantly, in line with the available scientific evidence (AU)
