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1.
Am J Rhinol Allergy ; 30(2): 149-54, 2016.
Article in English | MEDLINE | ID: mdl-26980397

ABSTRACT

BACKGROUND: Sinonasal inverted papilloma (SNIP), classically, is a unilateral benign tumor of the nasal lateral wall. Numerous variations have been observed, depending on location, bilateral presentation, or association with nasal polyposis. OBJECTIVE: The aim of this work was to describe atypical presentations of SNIPs with their management specificities and to assess their influence on the recurrence rate in a large case series. METHODS: A retrospective single center study of 110 patients treated for SNIP. Atypical inverted papillomas were identified according to the following criteria: (1) unusual location (frontal, posterior, anterior), (2) bilateral involvement, and (3) association with nasal polyposis. Surgical management was detailed, and the influence of each atypical group on recurrence was assessed by using Kaplan-Meier survival curves and the log-rank test. RESULTS: Distribution of atypical presentations was as follows: frontal sinus localization (10.9%); posterior localization, including sphenoid sinus (9%); nasal anterior localization (3.6%); bilateral involvement (3.6%); and nasal polyposis association (10%). The surgical approach was endoscopic (74.5%), external (5.5%), or combined endoscopic and external (20%). Except for nasal anterior localization, all the groups were associated with a higher recurrence rate, without reaching statistical significance. CONCLUSION: Recurrence rates for these atypical presentations arise from their specific surgical challenges. The choice of the surgical technique is guided by tumor location and extension, and by the surgeon's experience; the main objective is a complete resection. The endoscopic endonasal approach is the most frequent procedure.


Subject(s)
Frontal Sinus/surgery , Neoplasm Recurrence, Local/epidemiology , Papilloma, Inverted/physiopathology , Paranasal Sinus Neoplasms/physiopathology , Rhinoplasty , Adolescent , Adult , Aged , Aged, 80 and over , Disease Management , Endoscopy , Female , Follow-Up Studies , Humans , Male , Middle Aged , Papilloma, Inverted/epidemiology , Papilloma, Inverted/mortality , Paranasal Sinus Neoplasms/epidemiology , Paranasal Sinus Neoplasms/mortality , Retrospective Studies , Survival Analysis , Treatment Outcome , Young Adult
2.
Eur Ann Otorhinolaryngol Head Neck Dis ; 132(3): 153-6, 2015 Jun.
Article in English | MEDLINE | ID: mdl-25980627

ABSTRACT

Robot-assisted transaxillary thyroid surgery avoids the need for a neck incision. It consists of thyroid lobectomy and isthmectomy for moderately large unilateral benign nodules. The surgical imperatives are the same as for conventional surgery, but with differences in terms of patient positioning, surgical incision, equipment, surgical technique and indications. The purpose of this article is to describe the equipment, patient positioning and surgical technique of exclusive robot-assisted transaxillary total thyroid lobectomy and isthmectomy.


Subject(s)
Axilla/surgery , Robotics/methods , Thyroid Diseases/surgery , Thyroidectomy/methods , Feasibility Studies , Humans , Patient Satisfaction , Patient Selection , Thyroid Neoplasms/surgery , Treatment Outcome
3.
Eur Arch Otorhinolaryngol ; 271(4): 681-8, 2014 Apr.
Article in English | MEDLINE | ID: mdl-23539412

ABSTRACT

To evaluate the performance of the video head impulse test (VHIT) in assessing vestibular deficit in vestibular neuritis. Test validation study was conducted in Tertiary referral center. Twenty-nine patients, referred for vestibular neuritis between October 2009 and March 2012, were included. We recorded age, gender, values of caloric deficit (caloric testing), and deficits in semicircular function (VHIT) at initial presentation and at the follow-up visit (1-3 months). Multivariate linear regression analysis was performed to determine variables associated with values of caloric testing at the follow-up visit. Diagnostic values of VHIT were compared with caloric testing data using the receiver-operating characteristic (ROC) curve and subsequent statistical analysis. At the follow-up visit, complete recovery occurred in 31% of cases according to caloric evaluation, and VHIT normalized in 51.8%. Multivariate regression showed that a higher caloric deficit at the follow-up visit was associated with elevated age (p = 0.012) and high caloric deficit at initial presentation (p = 0.042). A lower caloric deficit was associated with normal VHIT results at the follow-up visit (p < 0.001). The ROC curve showed that specificity and sensitivity of VHIT were 100% when the caloric deficit was respectively lower than 40% or higher than 62.5%. At the caloric testing value of 30%, specificity was 100%, sensitivity 68.84%, positive predictive value 100% and negative predictive value 62.5%. VHIT is a fast, convenient and specific test to detect vestibular deficits in vestibular neuritis. However, VHIT lacks sensitivity by comparison with caloric testing, especially for moderate vestibular lesions.


Subject(s)
Head Impulse Test/methods , Vertigo/diagnosis , Vestibular Neuronitis/diagnosis , Adolescent , Adult , Age Factors , Aged , Caloric Tests/methods , Cohort Studies , Female , Humans , Linear Models , Male , Middle Aged , Multivariate Analysis , Prospective Studies , ROC Curve , Recovery of Function/physiology , Sensitivity and Specificity , Vertigo/etiology , Vertigo/physiopathology , Vestibular Neuronitis/complications , Vestibular Neuronitis/physiopathology , Video Recording/methods , Young Adult
4.
Eur J Cancer ; 46(2): 323-31, 2010 Jan.
Article in English | MEDLINE | ID: mdl-19931448

ABSTRACT

BACKGROUND: The tumour grading of primary parotid cancers (PPCs) remains controversial. METHODS: A 20-year standardised single centre treatment has been assessed retrospectively. The histological review of 155 consecutively treated parotid malignancies identified 96 suitable cases for univariate and multivariate survival analyses. RESULTS: Treatment involved total parotidectomy, neck dissection and post-operative radiotherapy in, respectively, 91.7%, 83.3% and 70.4% of cases. The 5-year overall survival, disease-specific and recurrence-free survival rates were 79.4%, 83.5% and 70.8%, respectively. Univariate analysis confirmed the classical prognostic factors, i.e. age>60 years, male gender, facial palsy, hardness of the tumour, clinical stage, tumour grade, facial nerve invasion and lymph node metastases. Multivariate analysis identified a three-grade classification just after the clinical stage as the most important prognostic factor. CONCLUSION: This study identifies the prognostic significance of intermediate grade tumours.


Subject(s)
Neck Dissection/methods , Neck Dissection/nursing , Parotid Gland/surgery , Parotid Neoplasms/pathology , Adolescent , Adult , Aged , Aged, 80 and over , Child , Female , Humans , Lymphatic Metastasis , Male , Middle Aged , Neoplasm Staging , Parotid Gland/pathology , Parotid Neoplasms/radiotherapy , Parotid Neoplasms/surgery , Postoperative Care/methods , Radiotherapy, Adjuvant , Retrospective Studies , Treatment Outcome , Young Adult
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