ABSTRACT
Keratoacanthoma generally occurs on the skin; it is rarely found in the conjunctiva. A case of a 34-year-old woman with a rapidly growing conjunctival mass is reported. The tumor was excised with a safety margin to exclude squamous cell carcinoma. Histopathologically it was crateriform and consistent with atypical keratoacanthoma. There has been no recurrence in 2 years of follow-up. Conjunctival keratoacanthoma is rare; differential diagnosis of conventional squamous cell carcinoma and keratoacanthoma can be difficult. We recommend complete surgical excision and careful follow-up of crateriform squamous proliferations.
Subject(s)
Conjunctival Diseases/surgery , Keratoacanthoma/surgery , Adult , Carcinoma, Squamous Cell/pathology , Conjunctival Diseases/pathology , Conjunctival Neoplasms/pathology , Diagnosis, Differential , Female , Humans , Keratoacanthoma/pathologyABSTRACT
The clinical triad of septo-optic dysplasia (SOD) comprises the abscence of the septum pellucidum, congenital optic nerve dysplasia, and multiple endocrine disorders. When any two of these factors are present, the condition is defined as an imcomplete form of SOD. The authors report the case of an imcomplete form of SOD in a 9-year old boy with low vision and nystagmus present from birth. The bilateral ophthalmoscopic examination revealed small papillae with double countour images. Magnetic resonance imaging showed hypoplasia of the optic nerve bilaterally, chiasm and absence of the septum pellucidum.
Subject(s)
Humans , Male , Child , Vision, Low/congenital , Optic Disk/abnormalities , Optic Disk/pathology , Optic Nerve Diseases/diagnosis , Septo-Optic Dysplasia/congenital , Optic Nerve/abnormalities , Optic Nerve/pathology , Nystagmus, Congenital , Septum Pellucidum/abnormalities , Septum Pellucidum/pathologyABSTRACT
Melkersson-Rosenthal syndrome is an uncommon disorder of uncertain aetiology characterized by orofacial oedema, facial nerve palsy and lingua plicata. The triad is seldom seen in its complete form, and oligo-symptomatic or mono-symptomatic forms are more common. An unusual case of Melkersson-Rosenthal syndrome involving the left upper eyelid is presented. The pathology, clinical features and management of this disorder are discussed.
Subject(s)
Edema/complications , Eyelid Diseases/complications , Melkersson-Rosenthal Syndrome/complications , Biopsy , Chronic Disease , Edema/diagnostic imaging , Eyelid Diseases/diagnostic imaging , Eyelids/pathology , Female , Humans , Melkersson-Rosenthal Syndrome/diagnosis , Middle Aged , Tomography, X-Ray ComputedABSTRACT
Ceratoacantoma geralmente ocorre na pele e raramente é encontrado na conjuntiva. Relatamos um caso de uma mulher de 34 anos que apresentou uma massa conjuntival de rápido crescimento. O tumor foi retirado com margem de segurança para excluir carcinoma de células escamosas. Ao exame histopatológico, o tumor apresentou configuração crateriforme, sendo consistente com ceratoacantoma atípico. Não houve recorrência após dois anos de seguimento. Ceratoacantoma conjuntival é uma doença rara. Um diagnóstico diferencial entre carcinoma de células escamosas e ceratoacantoma pode ser difícil. Recomendamos total remoção e seguimento cuidadoso de pacientes com lesões escamosas crateriformes.
Subject(s)
Adult , Female , Humans , Conjunctival Diseases/surgery , Keratoacanthoma/surgery , Carcinoma, Squamous Cell/pathology , Conjunctival Diseases/pathology , Conjunctival Neoplasms/pathology , Diagnosis, Differential , Keratoacanthoma/pathologyABSTRACT
PURPOSE: To report a patient with morning glory syndrome in combination with posterior pituitary ectopia and to emphasize the need for early recognition of this syndrome as an important step towards the diagnosis and treatment of the systemic anomalies that may be associated with it. METHODS: We present a 7-year-old boy who showed short stature, nystagmus, inward deviation and low vision. Ophthalmological and general physical examinations, further endocrine evaluation and magnetic resonance imaging (MRI) of the brain and sella turcica were performed. RESULTS: Both fundi showed symptoms of morning glory syndrome. The discs were pink and deeply excavated, and were surrounded by a ring of chorioretinal pigmentary disturbance. Magnetic resonance imaging revealed the absence of the infundibulum and posterior pituitary ectopia. Growth hormone studies confirmed the diagnosis of growth hormone deficiency. Therapy with recombinant human growth hormone was initiated. CONCLUSIONS: Although most cases of morning glory syndrome occur as isolated ocular abnormalities, it may occur in association with systemic anomalies, including posterior pituitary ectopia and hypopituitarism. A complete general physical examination and growth evaluation is important for early detection and treatment, resulting in benefit for these patients.
Subject(s)
Abnormalities, Multiple , Eye Abnormalities/complications , Hypopituitarism/congenital , Optic Disk/abnormalities , Pituitary Gland, Posterior/abnormalities , Child , Eye Abnormalities/diagnosis , Humans , Hypopituitarism/diagnosis , Magnetic Resonance Imaging , Male , Optic Disk/pathology , Pituitary Gland, Posterior/pathology , Pituitary Hormones/deficiency , Pituitary Hormones/therapeutic use , SyndromeABSTRACT
Infections due to Agrobacterium radiobacter are rare. This study reports 2 cases of A. radiobacter endophthalmitis. To the authors' knowledge, these are only the second and third reported cases of endophthalmitis caused by this Gram-negative rod.
