ABSTRACT
In this article the authors reconsider the literature about the drug treatment of sexual behaviour anomalies. In fact, the therapy of subjects convicted for sexual offences has been widely studied. The various drugs at disposal may be divided into three main groups: 1) oestrogens; 2) progesterone derivatives; 3) psycho-tropic-drugs. Among oestrogens the most widely used are oral stiboestrol and oestron. Recently, oestradio has been implanted subcutaneously. Even if effective all of them present some inconvenients, sometimes serious one, such as breast cancer. Recently drugs of the second group have been used. The most important of them is Cyproterone acetate, a synthetic substance, which is classified as antiandrogen and whose structure is like to progesterone. The effects in achieving a complete loss of libido and of sexual power have been judged satisfactory by all the authors who have experienced this drug. In U.S.A., where use of Cyproterone is still interdected, Medroxyprogersterone acetate is used parenterally and by depot with similar therapeutical effects. To the last group belong various drugs. The most used in benperidol, a neuroleptic, classified by many authors as antiandrogen.
