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1.
Making dragons: a speculative scientific adventure.
Pilcher, Helen.
Nature ; 2019 Aug 16.
Article in English | MEDLINE | ID: mdl-32801358
2.
Q&A: Peter Whorwell.
Pilcher, Helen.
Nature ; 533(7603): S112-3, 2016 05 19.
Article in English | MEDLINE | ID: mdl-27191490

Subject(s)
Irritable Bowel Syndrome , Amitriptyline/therapeutic use , Diet/adverse effects , Fecal Microbiota Transplantation , Humans , Hypnosis , Irritable Bowel Syndrome/diagnosis , Irritable Bowel Syndrome/microbiology , Irritable Bowel Syndrome/physiopathology , Irritable Bowel Syndrome/psychology , Irritable Bowel Syndrome/therapy , United Kingdom
3.
The egg and sperm race.
Pilcher, Helen.
New Sci ; 192(2574): 52-4, 2006.
Article in English | MEDLINE | ID: mdl-17165223

Subject(s)
Embryonic Stem Cells/cytology , Embryonic Stem Cells/physiology , Germ Cells/cytology , Germ Cells/physiology , Infertility/therapy , Reproductive Medicine/trends , Reproductive Techniques, Assisted/trends , Animals , Female , Humans , Male , Oocytes/cytology , Oocytes/physiology , Spermatozoa/cytology , Spermatozoa/physiology
4.
IVF in Africa: fertility on a shoestring.
Pilcher, Helen.
Nature ; 442(7106): 975-7, 2006 Aug 31.
Article in English | MEDLINE | ID: mdl-16943815

Subject(s)
Fertilization in Vitro/economics , Fertilization in Vitro/statistics & numerical data , Infertility/economics , Infertility/ethnology , Africa South of the Sahara/epidemiology , Africa South of the Sahara/ethnology , Female , Fertilization in Vitro/methods , Humans , Infertility/epidemiology , Infertility/therapy , Male
5.
Bioethics: dial 'E' for ethics.
Pilcher, Helen.
Nature ; 440(7088): 1104-5, 2006 Apr 27.
Article in English | MEDLINE | ID: mdl-16641966

Subject(s)
Bioethics/education , Bioethics/trends , Ethicists , Ethics, Research/education , Research Personnel/education , Research Personnel/ethics , Animals , Autistic Disorder , California , Ethicists/legislation & jurisprudence , Ethicists/standards , Humans , Research Personnel/legislation & jurisprudence , Twin Studies as Topic
6.
Gender gene implicated in Parkinson's disease.
Pilcher, Helen.
Lancet Neurol ; 5(4): 296, 2006 Apr.
Article in English | MEDLINE | ID: mdl-16578914

Subject(s)
Parkinson Disease/genetics , Sex Determination Processes , Animals , Brain/pathology , Brain/physiology , Female , Functional Laterality , Humans , Male
7.
Alzheimer's disease could be "type 3 diabetes".
Pilcher, Helen.
Lancet Neurol ; 5(5): 388-9, 2006 May.
Article in English | MEDLINE | ID: mdl-16639835

Subject(s)
Alzheimer Disease/physiopathology , Brain Chemistry , Diabetes Mellitus/physiopathology , Insulin/deficiency , Cell Survival , Humans , Neurons
8.
Alzheimer's mouse model raises treatment queries.
Pilcher, Helen.
Lancet Neurol ; 5(1): 28, 2006 Jan.
Article in English | MEDLINE | ID: mdl-16400739

Subject(s)
Alzheimer Disease/therapy , Disease Models, Animal , Alzheimer Disease/metabolism , Alzheimer Disease/pathology , Animals , Humans , Mice
9.
Parkin implicated in sporadic Parkinson's disease.
Pilcher, Helen.
Lancet Neurol ; 4(12): 798, 2005 Dec.
Article in English | MEDLINE | ID: mdl-16323352

Subject(s)
Parkinson Disease/metabolism , Ubiquitin-Protein Ligases/metabolism , Animals , Cell Death , Dopamine/metabolism , Humans , Neurons/metabolism , Parkinson Disease/pathology , Substantia Nigra/metabolism , Substantia Nigra/pathology
10.
Protein culprit found for transverse myelitis?
Pilcher, Helen.
Lancet Neurol ; 4(11): 702, 2005 Nov.
Article in English | MEDLINE | ID: mdl-16265794

Subject(s)
Myelitis, Transverse/chemically induced , Proteins/toxicity , Animals , Cell Death/drug effects , Cerebrospinal Fluid Proteins/chemistry , Cerebrospinal Fluid Proteins/toxicity , Humans , Interleukin-6/cerebrospinal fluid , Interleukin-6/toxicity , Myelitis, Transverse/pathology , Rats
11.
Microbiology: pipe dreams.
Pilcher, Helen.
Nature ; 437(7063): 1227-8, 2005 Oct 27.
Article in English | MEDLINE | ID: mdl-16251922

Subject(s)
Ammonia/metabolism , Bacteria/metabolism , Nitrogen/metabolism , Refuse Disposal/methods , Sewage/chemistry , Anaerobiosis , Animals , Bacteria/classification , Bacteria/cytology , Bioreactors , Netherlands , Organelles/metabolism , Oxidation-Reduction , Sewage/microbiology , Sulfides/metabolism
12.
Stem cells: natural born killers?
Pilcher, Helen.
Lancet Neurol ; 4(9): 527, 2005 Sep.
Article in English | MEDLINE | ID: mdl-16136700

Subject(s)
Apoptosis , Cell Communication , Neurons , Stem Cells/physiology , Cell Adhesion Molecules/biosynthesis , Gene Expression Regulation , Humans , Inflammation , Multiple Sclerosis/physiopathology , Multiple Sclerosis/prevention & control
13.
What the chimp means to me.
Pilcher, Helen; Check, Erika.
Nature ; 437(7055): 20-2, 2005 Sep 01.
Article in English | MEDLINE | ID: mdl-16136103

Subject(s)
Pan troglodytes/physiology , Pan troglodytes/psychology , Africa/epidemiology , Animal Communication , Animal Rights , Animals , Conservation of Natural Resources , Emotions , Female , Genomics , Hemorrhagic Fever, Ebola/epidemiology , Hemorrhagic Fever, Ebola/veterinary , Linguistics , Male , Pan troglodytes/genetics , Photography , Population Dynamics , Time Factors
14.
Parkinson's vaccine on trial.
Pilcher, Helen.
Lancet Neurol ; 4(8): 458-9, 2005 Aug.
Article in English | MEDLINE | ID: mdl-16086492

Subject(s)
Immunotherapy, Active , Parkinson Disease/therapy , Animals , Brain/pathology , Humans , Mice , Nerve Tissue Proteins/immunology , Parkinson Disease/immunology , Synucleins
15.
Rogue prions caught in action.
Pilcher, Helen.
Lancet Neurol ; 4(7): 397, 2005 Jul.
Article in English | MEDLINE | ID: mdl-15991434

Subject(s)
Prion Diseases/physiopathology , Prions/metabolism , Animals , Fluorescein , Humans , Prions/pathogenicity , Protein Transport/physiology
16.
Prion hypothesis proved?
Pilcher, Helen.
Lancet Neurol ; 4(6): 337, 2005 Jun.
Article in English | MEDLINE | ID: mdl-15931732

Subject(s)
Prion Diseases/etiology , Prions/toxicity , Animals , Brain/pathology , Cricetinae , Humans , Prion Diseases/transmission , Prions/administration & dosage
17.
Back to our roots.
Pilcher, Helen.
Nature ; 435(7045): 1022-3, 2005 Jun 23.
Article in English | MEDLINE | ID: mdl-15973376

Subject(s)
Phylogeny , Porifera/cytology , Porifera/physiology , Animals , Body Patterning , Carbon/metabolism , Cell Differentiation , Cell Movement , Fossils , History, Ancient , Models, Biological , Oxygen/metabolism , Porifera/embryology , Porifera/genetics , Research , Time Factors , Zoology
18.
Medicinal leeches: stuck on you.
Pilcher, Helen.
Nature ; 432(7013): 10-1, 2004 Nov 04.
Article in English | MEDLINE | ID: mdl-15525954

Subject(s)
Clinical Medicine/methods , Leeches/physiology , Osteoarthritis, Knee/therapy , Animals , Anti-Inflammatory Agents/analysis , Anti-Inflammatory Agents/therapeutic use , Anticoagulants/analysis , Anticoagulants/therapeutic use , Clinical Medicine/trends , Clinical Trials as Topic , Humans , Internationality , Leeches/chemistry , Saliva/chemistry
19.
Increasing virulence of bird flu threatens mammals.
Pilcher, Helen.
Nature ; 430(6995): 4, 2004 Jul 01.
Article in English | MEDLINE | ID: mdl-15229567

Subject(s)
Chickens/virology , Influenza, Human/transmission , Influenza, Human/veterinary , Mammals/virology , Orthomyxoviridae/pathogenicity , Animals , Ducks/virology , Evolution, Molecular , Humans , Influenza, Human/epidemiology , Influenza, Human/prevention & control , Mice , Orthomyxoviridae/genetics , Orthomyxoviridae/physiology , Virulence/genetics , Virulence/physiology
20.
Snapshot of a pandemic.
Pilcher, Helen.
Nature ; 430(6996): 134-5, 2004 Jul 08.
Article in English | MEDLINE | ID: mdl-15241383

Subject(s)
HIV Infections/epidemiology , Africa/epidemiology , Asia/epidemiology , Caribbean Region/epidemiology , Europe, Eastern/epidemiology , HIV Infections/mortality , HIV Infections/transmission , Humans
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