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1.
J Vasc Surg ; 59(5): 1217-23, 2014 May.
Article in English | MEDLINE | ID: mdl-24423480

ABSTRACT

OBJECTIVE: Open surgical repair (OSR) for chronic type B aortic dissection (CTBAD) has an associated morbidity and mortality. The role of thoracic endovascular aortic repair (TEVAR) in CTBAD has not been determined. We analyzed our contemporary experience of CTBAD undergoing OSR to identify high-risk patients who may be considered for TEVAR. METHODS: From 1999 to 2010, 221 patients had repair of descending thoracic and thoracoabdominal aortic aneurysms, including 86 patients with CTBADs. We analyzed this cohort for mortality, complications, length of stay, and reinterventions. RESULTS: OSR was performed in 25 (29%) and 61 (71%) patients for descending thoracic and thoracoabdominal CTBAD, respectively. Median age was 57.0 years (interquartile range [IQR], 52.0-64.2 years), and median diameter was 6.0 cm (IQR, 5.0-6.9 cm). Fifty-nine patients (69%) were male. Eight (9%) were treated for rupture. Follow-up duration was 4.6 years (IQR, 2.8-6.9 years). Hospital mortality occurred in five patients (5.8%). Cardiopulmonary bypass was used in 83 patients (97%) and deep hypothermic arrest in 36 (42%). Two patients (2.3%) each developed paraplegia, stroke, and renal failure requiring permanent hemodialysis in the postoperative period. Length of stay was 13.5 days (IQR, 10.0-21.0 days). Univariate predictors of hospital death included redo operations and prolonged pump time (P < .05). Six patients (7%) had aortic-related reoperations at 4.3 years (IQR, 2.7-5.2 years): one for an ascending aortic aneurysm and five for descending aortic aneurysms. Overall survival at 1, 5, and 7 years was 92%, 83%, and 70%, respectively, and freedom from reoperation was 99%, 90%, and 86%, respectively. CONCLUSIONS: OSR of CTBAD is a durable option with low mortality. Patients requiring redo operations or anticipated prolonged pump time need further evaluation to determine whether conventional OSR or TEVAR, if feasible, is the optimal treatment option.


Subject(s)
Aortic Aneurysm, Abdominal/surgery , Aortic Aneurysm, Thoracic/surgery , Aortic Dissection/surgery , Blood Vessel Prosthesis Implantation , Aortic Dissection/diagnosis , Aortic Dissection/mortality , Aortic Aneurysm, Abdominal/diagnosis , Aortic Aneurysm, Abdominal/mortality , Aortic Aneurysm, Thoracic/diagnosis , Aortic Aneurysm, Thoracic/mortality , Blood Vessel Prosthesis Implantation/adverse effects , Blood Vessel Prosthesis Implantation/mortality , Chronic Disease , Female , Hospital Mortality , Humans , Kaplan-Meier Estimate , Length of Stay , Male , Middle Aged , Patient Selection , Postoperative Complications/mortality , Postoperative Complications/surgery , Registries , Reoperation , Retrospective Studies , Risk Factors , Time Factors , Treatment Outcome
2.
Cardiovasc Pathol ; 15(3): 150-2, 2006.
Article in English | MEDLINE | ID: mdl-16697928

ABSTRACT

Aneurysms of the coronary arteries are uncommon occurrences that usually develop secondary to atherosclerosis and are often asymptomatic. They are usually diagnosed incidentally during investigation for ischemic heart disease or at autopsy for sudden death. We present a case of a "giant" right coronary artery aneurysm (CAA) discovered incidentally at surgery. Pathological examination confirmed that this was a true aneurysm showing marked thinning of the media and fibrocalcific plaques with small, multifocal areas of lymphocytic infiltrates.


Subject(s)
Atherosclerosis/pathology , Coronary Aneurysm/pathology , Coronary Vessels/pathology , Atherosclerosis/complications , Atherosclerosis/surgery , Coronary Aneurysm/etiology , Coronary Aneurysm/surgery , Coronary Angiography , Coronary Vessels/surgery , Humans , Male , Middle Aged
3.
Ann Thorac Surg ; 78(6): 2169-71, 2004 Dec.
Article in English | MEDLINE | ID: mdl-15561065

ABSTRACT

Coronary artery occlusive disease that develops after an uncomplicated aortic valve replacement is well recognized. We present a case that required two further coronary operations and two salvage angioplasty procedures for a continuing fibrotic process in the ascending aorta. The literature and pathology are reviewed.


Subject(s)
Coronary Stenosis/etiology , Heart Valve Prosthesis/adverse effects , Aged , Angina, Unstable/etiology , Aortic Valve/surgery , Aortic Valve Stenosis/surgery , Coronary Stenosis/diagnosis , Humans , Male
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