1.
Science
; 384(6701): 1163, 2024 Jun 14.
Article
in English
| MEDLINE
| ID: mdl-38870280
ABSTRACT
Steven Newmaster had been cleared, but fresh inquiry concludes he likely made up data.
2.
Science
; 384(6700): 1055, 2024 Jun 07.
Article
in English
| MEDLINE
| ID: mdl-38843339
ABSTRACT
The high-profile paper contains manipulated images, senior author acknowledges.
3.
Science
; 383(6688): 1165-1166, 2024 Mar 15.
Article
in English
| MEDLINE
| ID: mdl-38484070
ABSTRACT
Inspectors faulted analyses of clinical trial samples by Hoau-Yan Wang for drug developer Cassava Sciences.
Subject(s)
Alzheimer Disease , Scientific Misconduct , Spiro Compounds , United States Food and Drug Administration , Humans , Alzheimer Disease/drug therapy , Spiro Compounds/therapeutic use , United States , Clinical Trials as Topic
4.
Science
; 382(6672): 754-759, 2023 11 17.
Article
in English
| MEDLINE
| ID: mdl-37972193
ABSTRACT
Whistleblowers and former lab members suggest a star neuroscientist routinely manipulated data, compromising a planned NIH stroke trial and key Alzheimer's research.
Subject(s)
Alzheimer Disease , Scientific Misconduct , Stroke , Whistleblowing , Humans , Alzheimer Disease/therapy , Brain , Stroke/therapy , Clinical Trials as Topic , National Institutes of Health (U.S.)
5.
Science
; 382(6668): 251-252, 2023 10 20.
Article
in English
| MEDLINE
| ID: mdl-37856608
ABSTRACT
Co-developer of biotech's drug couldn't supply original data.
Subject(s)
Alzheimer Disease , Scientific Misconduct , Spiro Compounds , Humans , Alzheimer Disease/prevention & control , Biotechnology , United States
6.
Science
; 380(6641): 122-123, 2023 04 14.
Article
in English
| MEDLINE
| ID: mdl-37053319
ABSTRACT
Amyloid-clearing antibody lecanemab faces key FDA hearing in June.
Subject(s)
Alzheimer Disease , Amyloid beta-Peptides , Antibodies, Monoclonal, Humanized , Brain , Humans , Alzheimer Disease/drug therapy , Alzheimer Disease/mortality , Amyloid beta-Peptides/immunology , Antibodies, Monoclonal, Humanized/adverse effects , Antibodies, Monoclonal, Humanized/therapeutic use , Autopsy , Brain/pathology , Clinical Trials as Topic , Fear , United States Food and Drug Administration , Female , Aged
7.
Science
; 378(6624): 1030-1031, 2022 12 09.
Article
in English
| MEDLINE
| ID: mdl-36480604
ABSTRACT
Antibody slows cognitive decline, but deaths, brain bleeds, and swelling mar results.
Subject(s)
Alzheimer Disease , Antibodies, Monoclonal, Humanized , Apolipoprotein E4 , Humans , Alzheimer Disease/drug therapy , Alzheimer Disease/genetics , Apolipoprotein E4/genetics , Antibodies, Monoclonal, Humanized/therapeutic use , Randomized Controlled Trials as Topic
8.
Science
; 378(6621): 694-695, 2022 11 18.
Article
in English
| MEDLINE
| ID: mdl-36395231
ABSTRACT
Matthew Schrag confronts a mentor after their joint work is flagged on the PubPeer website.
Subject(s)
Neurosciences , Scientific Misconduct , Whistleblowing , Humans , Mentors , Neurosciences/ethics , Alzheimer Disease
9.
Science
; 377(6604): 363, 2022 07 22.
Article
in English
| MEDLINE
| ID: mdl-35862516
10.
Science
; 377(6604): 358-363, 2022 07 22.
Article
in English
| MEDLINE
| ID: mdl-35862524
ABSTRACT
A neuroscience image sleuth finds signs of fabrication in scores of Alzheimer's articles, threatening a reigning theory of the disease.
Subject(s)
Alzheimer Disease , Amyloid beta-Peptides , Blotting, Western , Scientific Misconduct , Alzheimer Disease/drug therapy , Alzheimer Disease/metabolism , Amyloid beta-Peptides/chemistry , Amyloid beta-Peptides/metabolism , Humans
11.
Science
; 377(6604): 363, 2022 07 22.
Article
in English
| MEDLINE
| ID: mdl-35862534
12.
Science
; 376(6598): 1145, 2022 06 10.
Article
in English
| MEDLINE
| ID: mdl-35679391
ABSTRACT
Report sees "insufficient evidence" of misconduct.
13.
Science
; 375(6580): 484-489, 2022 Feb 04.
Article
in English
| MEDLINE
| ID: mdl-35113716
ABSTRACT
[Figure: see text].
14.
Science
; 373(6556): 729-733, 2021 Aug 13.
Article
in English
| MEDLINE
| ID: mdl-34385377
Subject(s)
Asthma/drug therapy , Randomized Controlled Trials as Topic/ethics , Vitamin D/administration & dosage , Adolescent , Black or African American , Asthma/complications , Child , Clinical Trial Protocols as Topic , Comparative Effectiveness Research , Dietary Supplements , Ethics Committees, Research , Humans , Informed Consent , Placebos , Standard of Care , Symptom Flare Up , Vitamin D Deficiency/complications , Vitamin D Deficiency/drug therapy , Vitamins/administration & dosage
15.
Science
; 371(6527): 331-332, 2021 01 22.
Article
in English
| MEDLINE
| ID: mdl-33479130
16.
Science
; 370(6521): 1148-1149, 2020 12 04.
Article
in English
| MEDLINE
| ID: mdl-33273081
17.
Science
; 370(6512): 24-29, 2020 Oct 02.
Article
in English
| MEDLINE
| ID: mdl-33004497
18.
Science
; 370(6512): 27, 2020 Oct 02.
Article
in English
| MEDLINE
| ID: mdl-33004498
19.
Science
; 370(6515): 394-399, 2020 Oct 23.
Article
in English
| MEDLINE
| ID: mdl-33093092
20.
Science
; 370(6515): 396, 2020 Oct 23.
Article
in English
| MEDLINE
| ID: mdl-33093093
