1.
Pharmazie
; 49(1): 63-4, 1994 Jan.
Article
in English
| MEDLINE
| ID: mdl-8140132
Subject(s)
Acetamides/chemical synthesis , Acetonitriles/chemical synthesis , Analgesics/chemical synthesis , Benzoxazoles/chemical synthesis , Acetamides/pharmacology , Acetonitriles/pharmacology , Analgesics/pharmacology , Animals , Benzoxazoles/pharmacology , Female , Mice , Molecular Weight , Pain Measurement/drug effects , Spectrophotometry, Ultraviolet
2.
Arch Pharm (Weinheim)
; 326(9): 559-61, 1993 Sep.
Article
in English
| MEDLINE
| ID: mdl-8239947
ABSTRACT
Amongst a number of mesoionic compounds studied so far, sydnones have attained importance due not only to their structural features and chemical properties, but also to their biological properties. Sydnone derivatives have been extensively studied for their biological activities, the antimicrobial activity of substituted aryl sydnones has been reported. Aryl sydnones are less toxic and more active than alkyl sydnones. Also chalcone analogues are known to have antimicrobial activity.