ABSTRACT
PURPOSE: To describe and correlate with age the histopathologic findings observed in a group of specimens obtained from patients who underwent high condylectomy. MATERIALS AND METHODS: In this cross-sectional study, 27 condylar specimens from patients with facial asymmetry, suspected condylar hyperplasia (CH), and a positive diagnosis by single photon emission computed tomography (SPECT) were evaluated. Histopathologic variables measured in the mandibular condyles were thickness of fibrous, proliferative, and hyperplasic cartilage layers and total tissue thickness. RESULTS: The thickness of the fibrous layer (P = .014) and proliferative layer (P = .005) and total thickness (P = .007) were significantly greater in the patients studied compared with the literature reference values, and 66.6% of cases presented cartilage islands in the calcified region. Seventeen patients no older than 22 years (85%) showed this finding, whereas only 1 patient at least 23 years old did. Therefore, the presence of cartilage islands was significantly related to age (P = .001). CONCLUSIONS: Altogether, the histopathologic findings are consistent with the positive SPECT diagnosis of CH. Histopathologic evaluation showed an increased thickness in the soft tissue layer of the affected mandibular condyle, which was particularly marked for the proliferative layer. Cartilage islands were found mostly in patients no older than 22 years. Therefore, it is not a reliable pathognomic sign for CH because it could be related to normal condylar growth.
Subject(s)
Mandibular Condyle/pathology , Mandibular Diseases/pathology , Mandibular Osteotomy , Tomography, Emission-Computed, Single-Photon , Adolescent , Adult , Age Factors , Cartilage/pathology , Child , Cross-Sectional Studies , Diphosphonates , Female , Humans , Hyperplasia , Male , Mandibular Condyle/diagnostic imaging , Mandibular Condyle/surgery , Mandibular Diseases/diagnostic imaging , Mandibular Diseases/surgery , Radiopharmaceuticals , Technetium , Tomography, Emission-Computed, Single-Photon/methods , Young AdultABSTRACT
Resumen Se realizó un estudio descriptivo tipo reporte de caso de un paciente valorado por el servicio de gastroenterología en la Clínica Nuestra en la ciudad de Cali, por sospecha de sangrado digestivo oculto cuyos estudios previos no habían mostrado causa de sangrado. Se realizó videocápsula endoscópica (MiroCam®) con un hallazgo positivo de lesión en el intestino delgado. Se llevó a enteroscopia en Clínica Farallones de la Ciudad de Cali con enteroscopio Olympus 180 Q que confirmó el hallazgo. Ulteriormente, se llevó a cirugía, en la que se confirmó el diagnóstico. Los datos y las fotografías se obtuvieron en bases de datos de los servicios de endoscopia y las fotos de patología se obtuvieron del registro del médico patólogo. Finalmente, se realizó una búsqueda en PubMed sobre literatura existente de historia clínica y reportes de casos similares.
Abstract This is a descriptive study based on the case report of a patient suspected of occult gastrointestinal bleeding who was evaluated by the gastroenterology service in Clínica Nuestra in Cali. Previous studies had not shown cause of bleeding. Video endoscopy (Mirocam) found a lesion in the small intestine. Enteroscopy at performed at Clínica Farallones in Cali with an Olympus 180 Q enteroscope confirmed the finding. Surgery further confirmed the diagnosis. Data and photographs were obtained from the database of endoscopy services and the pathology photos were obtained from the pathologist's registry. A literature review based on a Pubmed search of the existing literature on clinical histories and reports of similar cases is included.
