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1.
BMJ Open ; 7(11): e016112, 2017 Nov 14.
Article in English | MEDLINE | ID: mdl-29138197

ABSTRACT

OBJECTIVE: This cohort study evaluates the unknown age-specific and gender-specific incidence of primary shoulder dislocations in the UK. SETTING: UK primary care data from the Clinical Practice Research Datalink (CPRD) were used to identify patients aged 16-70 years with a shoulder dislocation during 1995-2015. Coding of primary shoulder dislocations was validated using the CPRD general practitioner questionnaire service. PARTICIPANTS: A cohort of 16 763 patients with shoulder dislocation aged 16-70 years during 1995-2015 were identified. PRIMARY OUTCOME MEASURE: Incidence rates per 100 000 person-years and 95% CIs were calculated. RESULTS: Correct coding of shoulder dislocation within CPRD was 89% (95% CI 83% to 95%), and confirmation that the dislocation was a 'primary' was 76% (95% CI 67% to 85%). Seventy-two percent of shoulder dislocations occurred in men. The overall incidence rate in men was 40.4 per 100 000 person-years (95% CI 40.4 to 40.4), and in women was 15.5 per 100 000 person-years (95% CI 15.5 to 15.5). The highest incidence was observed in men aged 16-20 years (80.5 per 100 000 person-years; 95% CI 80.5 to 80.6). Incidence in women increased with age to a peak of 28.6 per 100 000 person-years among those aged 61-70 years. CONCLUSIONS: This is the first time the incidence of shoulder dislocations has been studied using primary care data from a national database, and the first time the results for the UK have been produced. While most primary dislocations occurred in young men, an unexpected finding was that the incidence increased in women aged over 50 years, but not in men. The reasons for this are unknown. Further work is commissioned by the National Institute for Health Research to examine treatments and predictors for recurrent shoulder dislocation. STUDY REGISTRATION: The design of this study was approved by the Independent Scientific Advisory Committee (15_260) for the Medicines & Healthcare products Regulatory Agency.


Subject(s)
Databases, Factual , Shoulder Dislocation/epidemiology , Adolescent , Adult , Age Factors , Aged , Cohort Studies , Data Accuracy , Databases, Factual/standards , Female , Humans , Incidence , Male , Middle Aged , Sex Factors , United Kingdom/epidemiology , Young Adult
2.
Qual Life Res ; 22(3): 665-75, 2013 Apr.
Article in English | MEDLINE | ID: mdl-22528239

ABSTRACT

PURPOSE: To assess different mapping methods for the estimation of a group's mean EQ-5D score based on responses to the Oxford hip score (OHS) questionnaire. METHODS: Four models were considered: a) linear regression using total OHS as a continuous regressor; b) linear regression employing responses to the twelve OHS questions as categorical predictors; c) two-part approach combining logistic and linear regression; and d) response mapping. The models were internally validated on the estimation data set, which included OHS and EQ-5D scores for total hip replacements, both before and six months after procedure for 1,759 operations. An external validation was also performed. RESULTS: All models estimated the mean EQ-5D score within 0.005 of an observed health-state utility estimate, ordinary least squares (OLS) continuous being the most accurate and OLS categorical the most consistent. Age, gender and deprivation did not improve the models. More accurate estimations at the individual level were achieved for higher scores of observed OHS and EQ-5D. CONCLUSION: Based on these results, when EQ-5D scores are not available, answers to the OHS questionnaire can be used to estimate a group's mean EQ-5D with a high degree of accuracy.


Subject(s)
Arthroplasty, Replacement, Hip/psychology , Quality of Life/psychology , Surveys and Questionnaires , Adult , Algorithms , Female , Humans , Least-Squares Analysis , Longitudinal Studies , Male , Predictive Value of Tests , Regression Analysis , Reproducibility of Results
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