Subject(s)
Breast Neoplasms , Sentinel Lymph Node , Axilla/pathology , Breast Neoplasms/pathology , Female , Humans , Immunohistochemistry , Intraoperative Period , Lymph Nodes/pathology , Sensitivity and Specificity , Sentinel Lymph Node/pathology , Sentinel Lymph Node/surgery , Sentinel Lymph Node Biopsy , TouchABSTRACT
AIM: To determine the diagnostic value and major complications of fine-needle aspiration (FNA) for primary liver cancer (PLC) and its influence on the treatment outcome and prognosis. METHODS: Information was gathered retrospectively for 3011 patients who presented with suspected PLC. Of which 2528 cases underwent ultrasound-guided fine-needle aspiration (US-FNA) biopsy. Patients were followed up through repeated office visits and imaging studies with a median follow-up of 7 months (range, 1-29 months). RESULTS: The sensitivity, specificity, positive predictive value, negative predictive value and overall accuracy of cytological diagnosis by FNA biopsy for detection of liver malignancy were 91.5%, 100.0%, 100.00%, 59.1% and 92.4% respectively. All patients with AFP> or = 400 microg/L were associated with malignancy. Of 1154 patients with AFP<400 microg/L who were finally proved PLC, 945 were detected by FNA alone. Major complications included bleeding in 11 cases (5 of them died later), occurred mainly in hepatocellular carcinoma with superficial location, large tumors and severe cirrhosis, and implantation metastases in 5 cases, which were recognized as a subcutaneous nodule at the previous biopsy site. Implantation metastases were treated with resection or radiotherapy. CONCLUSION: FNA biopsy is valuable for the diagnosis of PLC. However, complications of post-biopsy hemorrhage should not be ignored, as such bleeding may be fatal. Implantation seems to have little effect on the prognosis.
Subject(s)
Biopsy, Fine-Needle/adverse effects , Carcinoma, Hepatocellular/pathology , Hemorrhage/etiology , Liver Neoplasms/pathology , Carcinoma, Hepatocellular/blood , China , Female , Humans , Liver Neoplasms/blood , Liver Neoplasms/therapy , Male , Predictive Value of Tests , Retrospective Studies , Sensitivity and Specificity , Treatment Outcome , alpha-Fetoproteins/analysisSubject(s)
Breast Neoplasms/diagnosis , Carcinoma, Ductal, Breast/diagnosis , Genes, erbB-2 , Antibodies, Monoclonal/therapeutic use , Antibodies, Monoclonal, Humanized , Antineoplastic Agents/therapeutic use , Breast Neoplasms/drug therapy , Breast Neoplasms/genetics , Carcinoma, Ductal, Breast/drug therapy , Carcinoma, Ductal, Breast/genetics , Chromogenic Compounds , Female , Humans , In Situ Hybridization/methods , Patient Selection , TrastuzumabSubject(s)
Stents , Suture Techniques/instrumentation , Tricuspid Valve Insufficiency/surgery , Adult , Echocardiography , Equipment Design , Follow-Up Studies , Hemodynamics , Humans , Middle Aged , Rheumatic Heart Disease/complications , Severity of Illness Index , Thermodilution , Treatment Outcome , Tricuspid Valve Insufficiency/classification , Tricuspid Valve Insufficiency/diagnosis , Tricuspid Valve Insufficiency/microbiology , Tricuspid Valve Insufficiency/physiopathologyABSTRACT
32 postoperative cases of gastric carcinoma were treated by traditional Chinese medicine (TCM) drugs for supporting healthy energy and removing blood stasis, and their therapeutic results were compared with those in the control group treated by western medicine. After 6 months of treatment, in the TCM group, the rate of metastatic recurrence was significantly reduced, and the level of ornithine decarboxylase was also markedly lowered. Therefore, it is considered that the action of anti-metastatic recurrence of TCM drugs in postoperative cases of gastric carcinoma is probably related to the lowered activity of ornithine decarboxylase.
