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Br J Dermatol ; 157(5): 1032-6, 2007 Nov.
Article in English | MEDLINE | ID: mdl-17854365

ABSTRACT

Post-kala-azar dermal leishmaniasis (PKDL) is a complication of visceral leishmaniasis (VL) observed mainly in Sudan and India where it follows treated VL in 50% and 10% of cases, respectively. We report a 46-year-old patient with acquired immune deficiency syndrome who, 7 months after diagnosis of VL, developed PKDL and uveal leishmaniasis following HAART-induced immune recovery. In southern Europe PKDL seems to be an emerging clinical presentation among human immunodeficiency virus (HIV)-infected patients experiencing HAART-induced immune recovery after a previous diagnosis of VL. The best treatment among HIV-infected patients remains to be determined.


Subject(s)
Leishmaniasis, Cutaneous/etiology , Leishmaniasis, Visceral/complications , Acquired Immunodeficiency Syndrome/drug therapy , Americas , Antiprotozoal Agents/therapeutic use , Antiretroviral Therapy, Highly Active , Asia , Humans , Italy/ethnology , Leishmaniasis, Cutaneous/drug therapy , Male , Middle Aged , Pentamidine/therapeutic use , Phosphorylcholine/analogs & derivatives , Phosphorylcholine/therapeutic use , Travel
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