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J Endod ; 44(11): 1714-1719, 2018 Nov.
Article in English | MEDLINE | ID: mdl-30266468

ABSTRACT

INTRODUCTION: SmearOFF (Vista Dental Products, Racine, WI) is an irrigation solution containing chlorhexidine (CHX), EDTA, and a surfactant. This study examined the chemical interaction of SmearOFF with sodium hypochlorite (NaOCl) on the dentin surface, specifically the formation of precipitate and/or parachloroanaline (PCA). METHODS: Dentin blocks prepared from human maxillary molars were mounted in resin. Dentinal tubules were exposed in a perpendicular orientation using an ultracryomicrotome. The blocks were divided into 2 groups: the CHX group, irrigation with 6% NaOCl, 17% EDTA, 6% NaOCl, and 2% CHX, and the SmearOFF group, irrigation with 6% NaOCl and SmearOFF. The dentin surface was analyzed with time-of-flight secondary ion mass spectrometry and X-ray photoelectron spectroscopy to determine the formation of precipitate or/and PCA on the surface of dentin. RESULTS: Precipitation with PCA and occlusion of the dentinal tubules were noted on the dentin surface in the CHX group. No precipitate and no PCA were detected on the surface of dentin in the SmearOFF group. CONCLUSIONS: Interaction of SmearOFF with NaOCl on the dentin surface did not result in the formation of precipitate or PCA.


Subject(s)
Chlorhexidine/chemistry , Dentin/metabolism , Dentin/pathology , Root Canal Irrigants/chemistry , Sodium Hypochlorite/chemistry , Aniline Compounds/metabolism , Chemical Precipitation , Chlorhexidine/adverse effects , Drug Interactions , Edetic Acid , Humans , Microscopy, Electron, Scanning , Root Canal Irrigants/adverse effects , Sodium Hypochlorite/adverse effects , Spectrometry, Mass, Secondary Ion , Surface Properties , Surface-Active Agents
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