EUV and Hard X-ray Hartmann Wavefront Sensing for Optical Metrology, Alignment and Phase Imaging.

For more than 15 years, Imagine Optic have developed Extreme Ultra Violet (EUV) and X-ray Hartmann wavefront sensors for metrology and imaging applications. These sensors are compatible with a wide range of X-ray sources: from synchrotrons, Free Electron Lasers, laser-driven betatron and plasma-based EUV lasers to High Harmonic Generation. In this paper, we first describe the principle of a Hartmann sensor and give some key parameters to design a high-performance sensor. We also present different applications from metrology (for manual or automatic alignment of optics), to soft X-ray source optimization and X-ray imaging.

Direct visualization of carbon nanotube degradation in primary cells by photothermal imaging.

Assessment of biodegradability of carbon nanotubes (CNTs) is a critically important aspect that needs to be solved before their translation into new biomedical tools. CNT biodegradation has been shown both in vitro and in vivo, but we are limited by the number of analytical techniques that can be used to follow the entire process. Photothermal imaging (PhI) is an innovative technique that enables the quantitative detection of nanometer-sized absorptive objects. In this study, we demonstrate that PhI allows the observation of the degradation process of functionalized multi-walled carbon nanotubes (MWCNTs) following their internalization by primary glial cells. The absence of interference from the biological matrix components, together with the possibility to combine PhI with other detection techniques (e.g. fluorescence, light or electron microscopy) validate the potential of this method to follow the fate and behavior of carbon nanostructures in a biological environment.

Three-dimensional imaging using continuously self-imaging gratings.

In this Letter, we propose a method to perform 3D imaging with a simple and robust imaging system only composed of a continuously self-imaging grating (CSIG) and a matrix detector. With a CSIG, the intensity pattern generated by an object source is periodic and propagation invariant, apart from a dilatation factor that depends on the distance of the object. We demonstrate, theoretically and experimentally, how to exploit this property to analyze a scene in three dimensions. Such an imaging system can be used, for example, for tomographic applications.

Regularized image reconstruction for continuously self-imaging gratings.

In this paper, we demonstrate two image reconstruction schemes for continuously self-imaging gratings (CSIGs). CSIGs are diffractive optical elements that generate a depth-invariant propagation pattern and sample objects with a sparse spatial frequency spectrum. To compensate for the sparse sampling, we apply two methods with different regularizations for CSIG imaging. The first method employs continuity of the spatial frequency spectrum, and the second one uses sparsity of the intensity pattern. The two methods are demonstrated with simulations and experiments.

Relevance of continuously self-imaging gratings for noise robust imagery.

We have designed miniaturized, simple, and robust cameras composed of a single diffractive optical element (DOE) that generates a continuously self-imaging (CSI) beam. Two different DOEs are explored: the J0 Bessel transmittance, characterized by a continuous optical transfer function (OTF) and the CSI grating (CSIG), characterized by a sparse OTF. In this Letter, we will analyze the properties of both DOEs in terms of radiometric performances. We will demonstrate that the noise robustness is enhanced for a CSIG, thanks to the sparsity of its OTF. A camera using this DOE has been made and experimental images are presented to illustrate the noise robustness.

Optimal conditions for using the binary approximation of continuously self-imaging gratings.

Diffractive Optical Elements (DOE), that generate a propagation-invariant transverse intensity pattern, can be used for metrology and imaging application because they provide a very wide depth of focus. However, exact implementation of such DOE is not easy, so we generally code the transmittance by a binary approximation. In this paper, we will study the influence of the binary approximation of Continuously Self-Imaging Gratings (CSIG) on the propagated intensity pattern, for amplitude or phase coding. We will thus demonstrate that under specific conditions, parasitic effects due to the binarization disappear and we retrieve the theoretical non-diffracting property of CSIG's.