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Rev Med Chil ; 138(7): 827-31, 2010 Jul.
Article in Spanish | MEDLINE | ID: mdl-21043077

ABSTRACT

BACKGROUND: Chronic Hashimoto Thyroiditis (CHT) is the main cause of hypothyroidism. AIM: To report a series of patients with CHT. MATERIAL AND METHODS: Retrospective analysis of a series of 27 men aged 38 +/- 14 years and 201 women aged 37 +/- 16 years, evaluated in the private offices of two of the authors. RESULT: Fifty six percent of patients only had unspecific symptoms at the moment of consultation, 50% had a family history of thyroid diseases and only 21% of women had a previous history of goiter. Eighty one percent of patients had clinical or subclinical hypothyroidism, 62% had both antithyroglobulin and antithyroid peroxidase positive antibodies and 13% had both antibodies negative. Only 1.4% of patients had a normal thyroid ultrasound examination. Patients were treated with levothyroxine at a mean dosage of 75 microg/day and 53% achieved an adequate TSH level. Six often patients operated due to nodules had a papillary carcinoma. CONCLUSIONS: CHT should be sought in the general population, especially those with a family history of thyroid disease. Thyroid ultrasound is seldom normal in patients with CHT. Thyroid substitution should be monitored periodically to achieve adequate TSH levels.


Subject(s)
Hashimoto Disease/diagnosis , Adult , Chronic Disease , Family , Female , Hashimoto Disease/blood , Hashimoto Disease/drug therapy , Humans , Hypothyroidism/epidemiology , Iodide Peroxidase/immunology , Male , Retrospective Studies
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