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1.
PLoS One ; 14(2): e0200862, 2019.
Article in English | MEDLINE | ID: mdl-30794565

ABSTRACT

Robot-assisted training is a promising tool under development for improving walking function based on repetitive goal-oriented task practice. The challenges in developing the controllers for gait training devices that promote desired changes in gait is complicated by the limited understanding of the human response to robotic input. A possible method of controller formulation can be based on the principle of bio-inspiration, where a robot is controlled to apply the change in joint moment applied by human subjects when they achieve a gait feature of interest. However, it is currently unclear how lower extremity joint moments are modulated by even basic gait spatio-temporal parameters. In this study, we investigated how sagittal plane joint moments are affected by a factorial modulation of two important gait parameters: gait speed and stride length. We present the findings obtained from 20 healthy control subjects walking at various treadmill-imposed speeds and instructed to modulate stride length utilizing real-time visual feedback. Implementing a continuum analysis of inverse-dynamics derived joint moment profiles, we extracted the effects of gait speed and stride length on joint moment throughout the gait cycle. Moreover, we utilized a torque pulse approximation analysis to determine the timing and amplitude of torque pulses that approximate the difference in joint moment profiles between stride length conditions, at all gait speed conditions. Our results show that gait speed has a significant effect on the moment profiles in all joints considered, while stride length has more localized effects, with the main effect observed on the knee moment during stance, and smaller effects observed for the hip joint moment during swing and ankle moment during the loading response. Moreover, our study demonstrated that trailing limb angle, a parameter of interest in programs targeting propulsion at push-off, was significantly correlated with stride length. As such, our study has generated assistance strategies based on pulses of torque suitable for implementation via a wearable exoskeleton with the objective of modulating stride length, and other correlated variables such as trailing limb angle.


Subject(s)
Ankle Joint/physiology , Gait/physiology , Hip Joint/physiology , Knee Joint/physiology , Lower Extremity/physiology , Walking Speed/physiology , Adult , Biofeedback, Psychology/physiology , Biomechanical Phenomena/physiology , Exercise Test , Exercise Therapy/instrumentation , Exercise Therapy/methods , Exoskeleton Device , Female , Humans , Kinetics , Male , Physical Conditioning, Human/instrumentation , Physical Conditioning, Human/methods , Robotics/methods , Torque , Walking/physiology , Young Adult
2.
IEEE Int Conf Rehabil Robot ; 2017: 270-275, 2017 07.
Article in English | MEDLINE | ID: mdl-28813830

ABSTRACT

Robot-assisted gait training is becoming increasingly common to support recovery of walking function after neurological injury. How to formulate controllers capable of promoting desired features in gait, i.e. goals, is complicated by the limited understanding of the human response to robotic input. A possible method to formulate controllers for goal-oriented gait training is based on the analysis of the joint torques applied by healthy subjects to modulate such goals. The objective of this work is to understand how sagittal plane joint torque is affected by two important gait parameters: gait speed (GS) and stride length (SL). We here present the results obtained from healthy subjects walking on a treadmill at different speeds, and asked to modulate stride length via visual feedback. Via principal component analysis, we extracted the global effects of the two factors on the peak-to-peak amplitude of joint torques. Next, we used a torque pulse approximation analysis to determine optimal timing and amplitude of torque pulses that approximate the SL-specific difference in joint torque profiles measured at different values of GS. Our results show a strong effect of GS on the torque profiles in all joints considered. In contrast, SL mostly affects the torque produced at the knee joint at early and late stance, with smaller effects on the hip and ankle joints. Our analysis generated a set of torque assistance profiles that will be experimentally tested using gait training robots.


Subject(s)
Biomechanical Phenomena/physiology , Exercise Therapy/methods , Lower Extremity/physiology , Robotics/methods , Walking Speed/physiology , Adult , Exercise Test , Female , Humans , Male , Torque , Walking/physiology , Young Adult
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