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C R Acad Hebd Seances Acad Sci D ; 284(16): 1597-600, 1977 Apr 25.
Article in French | MEDLINE | ID: mdl-17478

ABSTRACT

The N-acetyl-galactosaminyltransferase activity has been studied in the biological fluids of YC8-lymphoma bearing Balb/c mice. It is enhanced during tumor development from 1 to 30 times in peritoneal fluids and from 1 to 10 times in sera. This activity is nil in urines. Optimal requirements for activity have been determined. Results suggest the existence, during tumor process not only of an enhancement of enzymatic activity, but also of a new molecule synthesis, molecules which are endogenous acceptors for the enzyme.


Subject(s)
Fucosyl Galactose alpha-N-Acetylgalactosaminyltransferase/metabolism , Hexosyltransferases/metabolism , Lymphoma/enzymology , Animals , Ascitic Fluid/enzymology , Cations, Divalent , Fucosyl Galactose alpha-N-Acetylgalactosaminyltransferase/blood , Fucosyl Galactose alpha-N-Acetylgalactosaminyltransferase/urine , Hydrogen-Ion Concentration , Male , Mice , Neoplasms, Experimental/enzymology , Time Factors
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