Clinical prediction model for red cell blood transfusion in elective primary posterior lumbar spine fusion.

Overestimated the cross-match of preoperative PRC preparation for elective primary lumbar spinal fusion needs revision for cost-effectiveness. We aimed to develop a novel preoperative predictive model for appropriate PRC preparation. This clinical prediction model in a retrospective cohort was studied between January 2015 and September 2022. Multivariate logistic regression models were used to assess predictive variables. The logistic coefficient of each predictor generated scores to establish a predictive model. The area under the receiver operating characteristic curve (AuROC) was used to evaluate the model. The predictive performance was validated using bootstrapping techniques and externally validated in 102 independent cases. Among 416 patients, 178 (43%) required transfusion. Four final predictors: preoperative hematocrit level, laminectomy level, transforaminal lumbar interbody fusion level, and sacral fusion. When categorized into two risk groups, the positive predictive values for the low-risk score (≤ 4) were 18.4 (95% Cl 13.9, 23.6) and 83.9 (95% CI 77.1, 89.3) for the high-risk score (> 4). AuROC was 0.90. Internal validation (bootstrap shrinkage = 0.993) and external validation (AuROC: 0.91). A new model demonstrated exemplary performance and discrimination in predicting the appropriate preparation for PRC. This study should be corroborated by rigorous external validation in other hospitals and by prospective assessments.

Effects of Cemented Hip Stem Pre-heating on Stem Push-out Strength.

OBJECTIVE: To determine the effect on ultimate push-out load and cement-stem surface shear strength of thermally manipulating the cobalt-chromium-molybdenum (CoCrMo) alloy stems of bone cement-stem constructs. METHODS: Satin-finished CoCrMo alloy stems were allocated to the following three groups with the predetermined temperatures: T24, ambient (24 °C); T37, body (37 °C); and T44, pre-heated stem (>44 °C). They were then inserted into hand-mixed high viscosity bone cement. Ultimate push-out load to failure was assessed with a servo hydraulic testing machine and the surface shear strength calculated. Data were compared among groups using the Kruskal-Wallis with Dunn's test. A P value of less than 0.05 was considered statistically significant. RESULTS: According to Kruskal-Wallis analysis, ultimate push-out load and surface shear strength differed significantly between the groups (P = 0.001). The T37 and T44 groups had higher ultimate push-out loads and surface shear strengths than the T24 group (P = 0.04 and 0.001, respectively). However, there was no statistically significant difference in these two variables between the T37 and T44 groups (P = 0.08). CONCLUSIONS: Pre-heating CoCrMo alloy stems enhance the ultimate push-out load and surface shear strength in vitro. The suggested temperature is 37 °C. This technique is recommended for hip arthroplasty procedures.