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3.
Rev. esp. patol ; 49(1): 37-40, ene.-mar. 2016. ilus
Article in Spanish | IBECS | ID: ibc-149064

ABSTRACT

La infección por Helicobacter heilmannii (H. heilmannii) en humanos es un evento poco frecuente, si bien, es común encontrarla en animales domésticos. Suele causar gastritis crónica, de leve a moderada intensidad, siendo su principal diagnóstico diferencial la infección por Helicobacter pylori (H. pylori), del cual presenta rasgos morfológicos distintivos. En este artículo presentamos un caso de gastritis crónica causada por H. heilmannii, en una paciente de 17 años, con sintomatología de dispepsia. Se estudiaron biopsias gástricas antrales que mostraron un moderado infiltrado inflamatorio y en donde se identificaron microorganismos alargados, en forma de espiral, localizados en las luces glandulares y en el moco de superficie, compatibles con H. heilmannii. Dichos microorganismos mostraron una expresión positiva con la tinción de inmunohistoquímica para H. pylori. A partir de este caso se realiza una descripción de las características clínico-patológicas observadas en pacientes afectados por H. heilmannii (AU)


Helicobacter heilmannii (H. heilmannii) infection is common in domestic animals but is rare in humans, in whom it can cause mild to moderate chronic gastritis. Its distinctive morphology allows a differential diagnosis with a Helicobacter pylori (H. pylori) infection. We present a case of chronic gastritis caused by H. heilmannii in a 17-year-old patient with symptoms of dyspepsia. Gastric antral biopsies showed moderate inflammatory infiltrate and long corkscrew-shaped spiral microorganisms, located in gastric pits as well as in the superficial mucus layer suggestive of H. heilmannii infection. These organisms were positive for anti-H. pylori antibody. The clinical and pathological features of H. heilmannii infection are discussed together with a review of the literatura (AU)


Subject(s)
Humans , Female , Adolescent , Gastritis/diagnosis , Gastritis/etiology , Gastritis/pathology , Helicobacter heilmannii/isolation & purification , Helicobacter heilmannii/pathogenicity , Dyspepsia/complications , Proton Pumps/therapeutic use , Clarithromycin/therapeutic use , Amoxicillin/therapeutic use , Metronidazole/therapeutic use , Gastritis/microbiology , Gastritis/physiopathology , Immunohistochemistry/methods , Immunohistochemistry , Gastric Mucosa/microbiology , Gastric Mucosa
12.
Gastroenterol. hepatol. (Ed. impr.) ; 35(10): 700-703, Dic. 2012. ilus, tab
Article in Spanish | IBECS | ID: ibc-106508

ABSTRACT

Los perineuriomas intestinales son lesiones poco frecuentes del tracto gastrointestinal. En este estudio presentamos una serie de 9 casos hallados en la mucosa colónica y analizados desde el punto de vista clínico-patológico e inmunohistoquímico. De ellos, 5 fueron mujeres y 4 hombres con edades medias de 59,5 y 64 años, respectivamente. Todas las lesiones eran de un tamaño inferior a 1 cm y tuvieron una localización intramucosa, predominando las situadas en el colon distal. Las técnicas imnunohistoquímicas para Glut-1, claudina-1 y EMA fueron de gran utilidad para determinar la naturaleza de estas lesiones (AU)


Intestinal perineuriomas are uncommon tumors of the gastrointestinal tract. In thisstudy, we analyzed the clinicopathologic and immunohistochemical features of nine colonic perineuriomas. Five patients were women and four were men (median age 59.5 years and64 years, respectively). All lesions were smaller than 1 cm and were located intramucosally, mainly in the distal colon. Immunohistochemical techniques for Glut-1, claudin-1 and EMA were especially useful in characterizing these lesions (AU)


Subject(s)
Humans , Nerve Sheath Neoplasms/epidemiology , Colonic Neoplasms/epidemiology , Colonic Polyps/epidemiology , Colonoscopy
15.
Gastroenterol Hepatol ; 35(10): 700-3, 2012 Dec.
Article in Spanish | MEDLINE | ID: mdl-22749510

ABSTRACT

Intestinal perineuriomas are uncommon tumors of the gastrointestinal tract. In this study, we analyzed the clinicopathologic and immunohistochemical features of nine colonic perineuriomas. Five patients were women and four were men (median age 59.5 years and 64 years, respectively). All lesions were smaller than 1cm and were located intramucosally, mainly in the distal colon. Immunohistochemical techniques for Glut-1, claudin-1 and EMA were especially useful in characterizing these lesions.


Subject(s)
Colonic Neoplasms/pathology , Colonic Polyps/pathology , Nerve Sheath Neoplasms/pathology , Aged , Aged, 80 and over , Biomarkers, Tumor/analysis , Claudin-1/analysis , Colon/innervation , Colonic Neoplasms/chemistry , Colonic Neoplasms/diagnosis , Colonic Polyps/chemistry , Colonic Polyps/diagnosis , Diagnosis, Differential , Female , Ganglioneuroma/diagnosis , Glucose Transporter Type 1/analysis , Humans , Intestinal Mucosa/pathology , Male , Middle Aged , Mucin-1/analysis , Neoplasm Proteins/analysis , Nerve Sheath Neoplasms/chemistry , Nerve Sheath Neoplasms/diagnosis , Neurofibroma/diagnosis , Retrospective Studies
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